Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Butyric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.41 |
| ▸ | PPARG | P37231 | 7/20 | 0.41 |
| ▸ | PPARD | Q03181 | 7/20 | 0.41 |
| ▸ | PPARA | Q07869 | 7/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Valeric Acid SCHEMBL25305990 | 0.93 | AKR1B1 (0.47) | TSHRAKR1B1GPR84PPARGPPARD | |
| Propylene Glycol SCHEMBL443949 | 0.89 | TSHR (0.48) | FFAR3TSHRALDH1A1TDP1MEN1 | |
| Propylene Glycol SCHEMBL282614 | 0.87 | TSHR (0.50) | TSHRALDH1A1TDP1MEN1ALOX15 | |
| Butyric Acid SCHEMBL14777773 | 0.87 | FFAR3 (0.62) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL28251629 | 0.84 | FFAR3 (0.65) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Propylene Glycol SCHEMBL4954281 | 0.84 | TSHR (0.61) | TSHRTDP1MEN1KMT2AHSD17B10 | |
| Propylene Glycol SCHEMBL55673 | 0.84 | TSHR (0.61) | TSHRTDP1MEN1KMT2AHSD17B10 | |
| Butyric Acid SCHEMBL359821 | 0.84 | FFAR3 (0.65) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL1245758 | 0.84 | FFAR3 (0.65) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Propylene Glycol SCHEMBL3738772 | 0.84 | EPHX2 (0.44) | TSHRALDH1A1TDP1HSD17B10USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1300256-A1 | PRINTED MATTER, ITS APPLICATION AND PRODUCTION METHOD THEREFOR | Matsumoto Inc. (JP) | 2003-04-09 | — | — | EP | disclosed |
| US-20030054140-A1 | Printed matter, its application and production method therefor | MATSUMOTO INC. (JP) | 2003-03-20 | — | — | US | disclosed |