SCHEMBL7037593

SCHEMBL7037593

C#Cc1ccc(-c2ccc(O)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP3 P08254 2/20 0.58
ESR1 P03372 5/20 0.58
ESR2 Q92731 4/20 0.58
BCL2L1 Q07817 1/20 0.48
CA12 O43570 2/20 0.46
CA2 P00918 2/20 0.46
CA3 P07451 2/20 0.46
CA9 Q16790 2/20 0.46
CA14 Q9ULX7 2/20 0.46
CA6 P23280 1/20 0.46
ABL1 P00519 1/20 0.46
ABCB1 P08183 1/20 0.46
BCR P11274 1/20 0.46
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
ALOX5 P09917 1/20 0.42
NPC1 O15118 2/20 0.42
MAPT P10636 2/20 0.42
NFKB1 P19838 2/20 0.42
RAB9A P51151 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28674751 1.00 MMP3 (0.58) MMP3ESR1ESR2BCL2L1CA12
SCHEMBL218284 0.92
SCHEMBL139611 0.86 HDAC8 (0.50) MMP3CA12CA2CA9CA14
SCHEMBL139848 0.86 HDAC8 (0.50) MMP3CA12CA2CA9CA14
Water SCHEMBL11190539 0.83 HDAC8 (0.48) MMP3CA12CA2CA9CA14
SCHEMBL10481156 0.83 HDAC8 (0.48) MMP3CA12CA2CA9CA14
SCHEMBL17616890 0.80 KEAP1 (0.38) MMP3ESR1ESR2CA12CA2
SCHEMBL11426043 0.78 NR1H2 (0.64) MMP3ESR1ESR2CA12CA2
SCHEMBL7031637 0.78 ESR1 (0.64) ESR1ESR2CA12CA2CA3
SCHEMBL7035102 0.78 MEN1 (0.64) ESR1ESR2CA12CA2CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9243185-B2 Polymerizable monomer and liquid crystal material applied to display panel AU OPTRONICS CORP. (TW) 2016-01-26 US disclosed
US-9243185-B2 Polymerizable monomer and liquid crystal material applied to display panel AU OPTRONICS CORP. (TW) 2016-01-26 US disclosed
US-20140065323-A1 POLYMERIZABLE MONOMER AND LIQUID CRYSTAL MATERIAL APPLIED TO DISPLAY PANEL AU OPTRONICS CORP. (TW) 2014-03-06 US disclosed
US-20140065323-A1 POLYMERIZABLE MONOMER AND LIQUID CRYSTAL MATERIAL APPLIED TO DISPLAY PANEL AU OPTRONICS CORP. (TW) 2014-03-06 US disclosed
US-20110080551-A1 POLYMERIZABLE MONOMER AND LIQUID CRYSTAL MATERIAL APPLIED TO DISPLAY PANEL AU OPTRONICS CORP. (TW) 2011-04-07 US disclosed
US-20110080551-A1 POLYMERIZABLE MONOMER AND LIQUID CRYSTAL MATERIAL APPLIED TO DISPLAY PANEL AU OPTRONICS CORP. (TW) 2011-04-07 US disclosed
US-20030065117-A1 Modified silicone compound, process of producing the same, and cured object obtained therefrom NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2003-04-03 US disclosed
US-4221895-A POLYESTER, POLYSULFONATE, OR POLYSULFINATE THE DOW CHEMICAL COMPANY (US) 1980-09-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140065323-A1 POLYMERIZABLE MONOMER AND LIQUID CRYSTAL MATERIAL APPLIED TO DISPLAY PANEL SP1, ZYX, PYM1 MMP3 4130/4885ESR1 205/4885ESR2 1332/4885
US-20110080551-A1 POLYMERIZABLE MONOMER AND LIQUID CRYSTAL MATERIAL APPLIED TO DISPLAY PANEL SP1, ZYX, PYM1 MMP3 4130/4885ESR1 205/4885ESR2 1332/4885
US-20030065117-A1 Modified silicone compound, process of producing the same, and cured object obtained therefrom ORMDL3, SGMS1, HEATR1 MMP3 4301/4885ESR1 758/4885ESR2 961/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.