SCHEMBL7040059

SCHEMBL7040059

COC(=O)c1c(CBr)cccc1-c1ccc(C(F)(F)F)cc1

nearest known ligand 0.43

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
BDKRB1 P46663 14/20 0.43
FFAR1 O14842 1/20 0.43
FFAR4 Q5NUL3 1/20 0.43
BACE1 P56817 1/20 0.40
PTPN1 P18031 1/20 0.39
MRGPRX4 Q96LA9 1/20 0.39
AKR1C3 P42330 1/20 0.39
AKR1C2 P52895 1/20 0.39
SLC6A4 P31645 1/20 0.39
SLC6A3 Q01959 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30755131 1.00 BDKRB1 (0.43) BDKRB1FFAR1FFAR4BACE1PTPN1
SCHEMBL27371082 0.88 FFAR1 (0.42) BDKRB1FFAR1FFAR4BACE1PTPN1
SCHEMBL27362186 0.85 FFAR1 (0.44) BDKRB1FFAR1FFAR4BACE1PTPN1
SCHEMBL30307414 0.84 HTT (0.49) BDKRB1SLC6A3
SCHEMBL30755410 0.81 BACE1 (0.44) BDKRB1BACE1PTPN1SLC6A4SLC6A3
SCHEMBL7041867 0.81 BACE1 (0.44) BDKRB1BACE1PTPN1SLC6A4SLC6A3
SCHEMBL6674022 0.80 BACE1 (0.41) FFAR1FFAR4BACE1PTPN1AKR1C3
SCHEMBL5937242 0.80 NOTUM (0.47) PTPN1AKR1C3AKR1C2
SCHEMBL5199432 0.77 KIF11 (0.50) FFAR1FFAR4BACE1PTPN1
SCHEMBL9544732 0.77 CA12 (0.55)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260034123-A1 CDK2 INHIBITORS AND METHODS OF USING THE SAME CEDILLA THERAPEUTICS INC (US) 2026-02-05 US disclosed
WO-2024026483-A2 CDK2 INHIBITORS AND METHODS OF USING THE SAME CEDILLA THERAPEUTICS, INC. (US) 2024-02-01 WO disclosed
US-20030162788-A1 Combination of MTP inhibitors or apoB-secretion inhibitors with fibrates for use as pharmaceuticals BOEHRINGER INGELHEIM PHARMA KG (DE) 2003-08-28 US disclosed
US-20030073836-A1 Heteroarylcarboxylic acid amides, the preparation thereof and their use as pharmaceutical compositions BOEHRINGER INGELHEIM PHARMA KG (DE) 2003-04-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260034123-A1 CDK2 INHIBITORS AND METHODS OF USING THE SAME CDK2, CDK1, CDK20 BDKRB1 3773/4885FFAR1 3730/4885FFAR4 4178/4885
US-20030162788-A1 Combination of MTP inhibitors or apoB-secretion inhibitors with fibrates for use as pharmaceuticals APOB, LIPC, MTPN BDKRB1 2674/4885FFAR1 377/4885FFAR4 183/4885
US-20030073836-A1 Heteroarylcarboxylic acid amides, the preparation thereof and their use as pharmaceutical compositions MTTP, CETP, CES1 BDKRB1 2457/4885FFAR1 271/4885FFAR4 342/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.