SCHEMBL7041867

SCHEMBL7041867

COC(=O)c1c(C)cccc1-c1ccc(C(F)(F)F)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.44
CISD2 Q8N5K1 1/20 0.43
SLC6A4 P31645 1/20 0.42
SLC6A3 Q01959 1/20 0.42
PTPN1 P18031 1/20 0.42
FGFR1 P11362 1/20 0.42
FGFR2 P21802 1/20 0.42
FGFR4 P22455 1/20 0.42
FGFR3 P22607 1/20 0.42
HTT P42858 2/20 0.42
MEN1 O00255 1/20 0.42
MAPT P10636 1/20 0.42
RAB9A P51151 1/20 0.42
KMT2A Q03164 1/20 0.42
CFTR P13569 1/20 0.41
BDKRB1 P46663 6/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30755410 1.00 BACE1 (0.44) BACE1CISD2SLC6A4SLC6A3PTPN1
SCHEMBL27371068 0.86 APP (0.43) BACE1HTTMEN1MAPTRAB9A
SCHEMBL6497035 0.84 BACE1 (0.47) BACE1HTTMEN1MAPTRAB9A
SCHEMBL4827133 0.82 HTT (0.58) SLC6A4SLC6A3FGFR1FGFR2FGFR4
SCHEMBL30755131 0.81 BDKRB1 (0.43) BACE1SLC6A4SLC6A3PTPN1BDKRB1
SCHEMBL7040059 0.81 BDKRB1 (0.43) BACE1SLC6A4SLC6A3PTPN1BDKRB1
SCHEMBL70172 0.81 CA12 (0.59) FGFR1FGFR2FGFR4FGFR3HTT
SCHEMBL8542008 0.81 SLC6A3 (0.59) SLC6A4SLC6A3FGFR1FGFR2FGFR4
SCHEMBL29917415 0.80 SLC6A3 (0.52) BACE1SLC6A4SLC6A3PTPN1CFTR
SCHEMBL10058722 0.79 CFTR (0.47) BACE1CISD2PTPN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260034123-A1 CDK2 INHIBITORS AND METHODS OF USING THE SAME CEDILLA THERAPEUTICS INC (US) 2026-02-05 US disclosed
WO-2024026483-A2 CDK2 INHIBITORS AND METHODS OF USING THE SAME CEDILLA THERAPEUTICS, INC. (US) 2024-02-01 WO disclosed
US-20030162788-A1 Combination of MTP inhibitors or apoB-secretion inhibitors with fibrates for use as pharmaceuticals BOEHRINGER INGELHEIM PHARMA KG (DE) 2003-08-28 US disclosed
US-20030073836-A1 Heteroarylcarboxylic acid amides, the preparation thereof and their use as pharmaceutical compositions BOEHRINGER INGELHEIM PHARMA KG (DE) 2003-04-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260034123-A1 CDK2 INHIBITORS AND METHODS OF USING THE SAME CDK2, CDK1, CDK20 BACE1 2774/4885CISD2 988/4885SLC6A4 4399/4885
US-20030162788-A1 Combination of MTP inhibitors or apoB-secretion inhibitors with fibrates for use as pharmaceuticals APOB, LIPC, MTPN BACE1 722/4885CISD2 3108/4885SLC6A4 2194/4885
US-20030073836-A1 Heteroarylcarboxylic acid amides, the preparation thereof and their use as pharmaceutical compositions MTTP, CETP, CES1 BACE1 2768/4885CISD2 3642/4885SLC6A4 2700/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.