Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HRH1 | P35367 | 3/20 | 0.39 |
| ▸ | DRD3 | P35462 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 7/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7040690 | 0.79 | PIN1 (0.33) | CNR2ALDH1A1SMN1; SMN2GAAKMT2A | |
| SCHEMBL24171768 | 0.79 | CNR2 (0.41) | LMNAHRH1DRD3KCNH2HTR2A | |
| SCHEMBL7045044 | 0.78 | RORC (0.38) | LMNARORCCNR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL10071706 | 0.74 | GRIN2B (0.36) | PDE4AALOX15USP2ALDH1A1MEN1 | |
| SCHEMBL10169477 | 0.73 | LMNA (0.49) | LMNAHTR2AALOX15RORCCNR2 | |
| SCHEMBL11365553 | 0.72 | HRH1 (0.71) | LMNAHRH1DRD3KCNH2HTR2A | |
| Hydrochloric Acid SCHEMBL11378292 | 0.71 | HRH1 (0.72) | LMNAHRH1DRD3KCNH2HTR2A | |
| SCHEMBL5999820 | 0.71 | HRH1 (0.79) | LMNAHRH1DRD3KCNH2HTR2A | |
| SCHEMBL1968090 | 0.71 | HRH1 (0.79) | LMNAHRH1DRD3KCNH2HTR2A | |
| SCHEMBL5999809 | 0.71 | HRH1 (0.79) | LMNAHRH1DRD3KCNH2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0956286-B1 | SYNTHESIS OF TERFENADINE AND DERIVATIVES | SEPRACOR INC (US) | 2003-04-02 | — | — | EP | disclosed |
| US-6147217-A | Synthesis of terfenadine and derivatives | SEPRACOR INC. (US) | 2000-11-14 | — | — | US | disclosed |
| EP-0956286-A1 | SYNTHESIS OF TERFENADINE AND DERIVATIVES | SEPRACOR, INC. (US) | 1999-11-17 | — | — | EP | disclosed |
| WO-1998033789-A1 | SYNTHESIS OF TERFENADINE AND DERIVATIVES | SEPRACOR, INC. (US) | 1998-08-06 | — | — | WO | disclosed |