Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.54 |
| ▸ | CA9 | Q16790 | 4/20 | 0.54 |
| ▸ | CA12 | O43570 | 3/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP7 | P09237 | 1/20 | 0.45 |
| ▸ | MMP14 | P50281 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PARL | Q9H300 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL10325169 | 0.86 | CA2 (0.65) | CA2CA9CA12CA1PTPN1 | |
| SCHEMBL8662029 | 0.81 | CA12 (0.60) | CA2CA9CA12CA1ALDH1A1 | |
| Biphenyl SCHEMBL31301151 | 0.80 | CA1 (0.52) | CA2CA9CA12CA1PTPN1 | |
| SCHEMBL31124571 | 0.79 | PTPN1 (0.51) | CA2CA9CA12CA1PTPN1 | |
| Sulfuric Acid SCHEMBL29279046 | 0.79 | ALDH1A1 (0.56) | CA2CA9CA12CA1PTPN1 | |
| Sulfamide SCHEMBL28796033 | 0.79 | CA2 (0.64) | CA2CA9CA12CA1ALDH1A1 | |
| SCHEMBL15879480 | 0.79 | ALDH1A1 (0.56) | CA2CA9CA12CA1ALDH1A1 | |
| Benzene SCHEMBL6886142 | 0.77 | TSHR (0.46) | CA2CA9CA12CA1PTPN1 | |
| Benzene SCHEMBL1584200 | 0.77 | TSHR (0.46) | CA2CA9CA12CA1PTPN1 | |
| SCHEMBL8463 | 0.77 | ALDH1A1 (0.90) | CA2CA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1295602-A1 | OXYGEN-CONTAINING OPHTHALMIC COMPOSITION | ROHTO PHARMACEUTICAL CO., LTD. (JP) | 2003-03-26 | — | — | EP | disclosed |
| US-20020164379-A1 | Oxygen-containing ophthalmic composition | ROHTO PHARMACEUTICAL CO., LTD. (JP) | 2002-11-07 | — | — | US | disclosed |
| CN-1291898-A | Remedies for corneal epithelium disturbance | WAKAMOTO PHARMA CO LTD (JP) | 2001-04-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020164379-A1 | Oxygen-containing ophthalmic composition | OGFOD1, HIF1A, HAO2 | CA2 238/4885CA9 542/4885CA12 2041/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.