Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | PLK1 | P53350 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | GCK | P35557 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7040701 | 0.84 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2RECQLHSD17B10TSHR | |
| SCHEMBL6184019 | 0.79 | KMT2A (0.39) | ALDH1A1RECQLHSD17B10TSHRNAPRT | |
| SCHEMBL9845992 | 0.74 | MTNR1A (0.37) | ALDH1A1SMN1; SMN2HSD17B10TSHRNAPRT | |
| SCHEMBL15514000 | 0.73 | PTPN1 (0.38) | ALDH1A1SMN1; SMN2TSHRNPC1RAB9A | |
| SCHEMBL13922742 | 0.71 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2RECQLTSHRRAB9A | |
| SCHEMBL29126028 | 0.67 | TGM2 (0.44) | ALDH1A1SMN1; SMN2RAB9AGAACYP3A4 | |
| SCHEMBL2931057 | 0.67 | NAPRT (0.37) | ALDH1A1SMN1; SMN2HSD17B10NAPRTNPC1 | |
| SCHEMBL5778129 | 0.67 | KMT2A (0.44) | ALDH1A1SMN1; SMN2HSD17B10TSHRNAPRT | |
| SCHEMBL9781781 | 0.67 | NPC1 (0.61) | ALDH1A1NPC1RAB9AEPHX2 | |
| SCHEMBL9621660 | 0.66 | ALDH1A1 (0.44) | ALDH1A1HSD17B10TSHRNAPRTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003018019-A2 | NEW USE OF CYCLIC COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-03-06 | — | — | WO | disclosed |
| EP-1259499-A1 | THIAZEPINYL HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-27 | — | — | EP | disclosed |
| WO-2001060808-A1 | THIAZEPINYL HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-08-23 | — | — | WO | disclosed |