Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 4/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.45 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7044617 | 0.86 | GABRA2 (0.47) | ALOX15PDE3BPDE3AALOX5PTGES | |
| SCHEMBL7045705 | 0.81 | GABRA2 (0.46) | ALOX15ALOX5MAPTGAANPSR1 | |
| SCHEMBL7044707 | 0.79 | ALOX5 (0.52) | ALOX15PDE3BPDE3AALOX5PTGES | |
| SCHEMBL1918799 | 0.76 | MAPT (0.53) | PDE3BPDE3AMAPTKDM4ECYP3A4 | |
| SCHEMBL6553466 | 0.74 | ALOX5 (0.51) | ALOX15ALOX5PTGESMAPTKDM4E | |
| SCHEMBL27858959 | 0.73 | NPSR1 (0.48) | ALOX15PDE3BPDE3AKDM4ECYP3A4 | |
| SCHEMBL7044205 | 0.73 | CNR1 (0.52) | MAPTALDH1A1LMNAHTT | |
| SCHEMBL7042633 | 0.73 | CNR1 (0.52) | — | |
| SCHEMBL14109406 | 0.72 | MAPT (0.57) | PDE3BPDE3AMAPTKDM4EGAA | |
| SCHEMBL18796691 | 0.72 | PDE3B (0.70) | ALOX15PDE3BPDE3AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007887-A2 | SUBSTITUTED IMIDAZOLES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-01-30 | — | — | WO | disclosed |