Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.52 |
| ▸ | PTGES | O14684 | 2/20 | 0.51 |
| ▸ | CDC7 | O00311 | 1/20 | 0.46 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6553466 | 0.86 | ALOX5 (0.51) | ALOX5PTGESCDC7DBF4MAPT | |
| SCHEMBL7044617 | 0.82 | GABRA2 (0.47) | ALOX5PTGESCDC7DBF4MAPT | |
| SCHEMBL7041804 | 0.79 | ALOX15 (0.47) | ALOX5PTGESMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL7045705 | 0.74 | GABRA2 (0.46) | ALOX5CDC7DBF4MAPTNPC1 | |
| SCHEMBL2871376 | 0.72 | KDM4E (0.46) | MAPTKDM4EPOLBSMN1; SMN2CNR1 | |
| SCHEMBL31305427 | 0.72 | KDM4E (0.46) | MAPTKDM4EPOLBSMN1; SMN2CNR1 | |
| SCHEMBL4468878 | 0.70 | CSF1R (0.55) | ALOX5CDC7DBF4MAPTKDM4E | |
| SCHEMBL7044592 | 0.70 | CDC7 (0.44) | CDC7DBF4MAPTCNR1DPP4 | |
| SCHEMBL4466647 | 0.69 | ADORA3 (0.52) | CDC7DBF4MAPTKDM4ENPC1 | |
| SCHEMBL7044437 | 0.69 | CNR1 (0.55) | POLBCNR1ALOX15TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007887-A2 | SUBSTITUTED IMIDAZOLES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-01-30 | — | — | WO | disclosed |