Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27796692 | 0.75 | NPC1 (0.41) | NPC1RAB9ASMN1; SMN2KMT2ATP53 | |
| SCHEMBL17527769 | 0.74 | L3MBTL1 (0.48) | CYP1A2CYP2C19NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27467512 | 0.73 | ALDH1A1 (0.50) | RAB9ASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL16756221 | 0.73 | SMN1; SMN2 (0.43) | CYP2C19NPC1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL28106320 | 0.71 | MTNR1A (0.36) | RAB9AALDH1A1MAPK1 | |
| SCHEMBL15549354 | 0.71 | ALOX15 (0.45) | NPC1RAB9ASMN1; SMN2KMT2ATP53 | |
| SCHEMBL7043280 | 0.71 | ALOX15 (0.47) | TOP2ARAB9ASMN1; SMN2HSD17B10KMT2A | |
| SCHEMBL6517546 | 0.70 | HPGD (0.45) | CYP2C9TOP2AKMT2AALDH1A1 | |
| SCHEMBL14340375 | 0.70 | HPGD (0.45) | TOP2AKMT2A | |
| SCHEMBL27830688 | 0.70 | CYP4F2 (0.42) | CYP1A2CYP2C9SMN1; SMN2HSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0967261-B1 | Liquid crystal compound having negative dielectric anisotropy, liquid crystal composition containing said liquid crystal compound and liquid crystal display device using said composition | CHISSO CORP (JP) | 2003-04-02 | — | — | EP | disclosed |
| EP-0967261-A1 | Liquid crystal compound having negative dielectric anisotropy, liquid crystal composition containing said liquid crystal compound and liquid crystal display device using said composition | Chisso Corporation (JP) | 1999-12-29 | — | — | EP | disclosed |