Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 4/20 | 0.37 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL707821 | 0.75 | HRH1 (0.40) | HRH1CACNA1FCHRM2CHRM1ADRA2B | |
| SCHEMBL95876 | 0.73 | SLC6A2 (0.47) | LMNATAAR1 | |
| SCHEMBL5079703 | 0.71 | HRH1 (0.52) | HRH1CACNA1FCHRM2CHRM1ADRA2B | |
| SCHEMBL5252028 | 0.70 | KCNA3 (0.39) | LMNATAAR1 | |
| SCHEMBL4980093 | 0.70 | ALDH1A1 (0.37) | MEN1KMT2ATAAR1TDP1ATM | |
| SCHEMBL11339531 | 0.70 | MAPK1 (0.38) | KCNH2KMT2ATAAR1 | |
| SCHEMBL131978 | 0.70 | MAPK1 (0.44) | MEN1KMT2ATAAR1TSHR | |
| SCHEMBL6779249 | 0.69 | — | — | |
| SCHEMBL97085 | 0.68 | TSHR (0.47) | KDM4EL3MBTL1TSHR | |
| SCHEMBL5046280 | 0.67 | TAAR1 (0.48) | HRH1CACNA1FCHRM2CHRM1ADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030176448-A1 | Mitochondria protecting agents for treating mitochondria associated diseases | MITOKOR (US) | 2003-09-18 | — | — | US | disclosed |
| US-6511966-B2 | Administering for therapy of mitochondria medited disease | MITOKOR | 2003-01-28 | — | — | US | disclosed |
| US-6498191-B2 | FOR TREATMENT OF ALZHEIMER'S DISEASE, DIABETES MELLITUS, PARKINSON'S DISEASE, NEURONAL AND CARDIAC ISCHEMIA, HUNTINGTON'S DISEASE, STROKE | MITOKOR | 2002-12-24 | — | — | US | disclosed |
| EP-1222920-A2 | Mitochondria protecting agents for treating mitochondria associated diseases | MITOKOR (US) | 2002-07-17 | — | — | EP | disclosed |
| US-20020068750-A1 | Mitochondria protecting agents for treating mitochondria associated diseases | GHOSH SOUMITRA S (US) | 2002-06-06 | — | — | US | disclosed |
| US-20020065298-A1 | Mitochondria protecting agents for treating mitochondria associated diseases | GHOSH SOUMITRA S (US) | 2002-05-30 | — | — | US | disclosed |
| US-20020065299-A1 | Mitochondria protecting agents for treating mitochondria associated diseases | GHOSH SOUMITRA S (US) | 2002-05-30 | — | — | US | disclosed |
| US-20020010195-A1 | Mitochondria protecting agents for treating mitochondria associated diseases | GHOSH SOUMITRA S (US) | 2002-01-24 | — | — | US | disclosed |
| EP-1051165-A2 | MITOCHONDRIA PROTECTING AGENTS FOR TREATING MITOCHONDRIA ASSOCIATED DISEASES | Mitokor (US) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999037294-A2 | MITOCHONDRIA PROTECTING AGENTS FOR TREATING MITOCHONDRIA ASSOCIATED DISEASES | MITOKOR (US) | 1999-07-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020065298-A1 | Mitochondria protecting agents for treating mitochondria associated diseases | TFAM, HSPA9, HSPD1 | HRH1 3806/4885CACNA1F 2335/4885CHRM2 3133/4885 |
| US-20030176448-A1 | Mitochondria protecting agents for treating mitochondria associated diseases | TFAM, HSPA9, HSPD1 | HRH1 3825/4885CACNA1F 2364/4885CHRM2 3165/4885 |
| US-20020068750-A1 | Mitochondria protecting agents for treating mitochondria associated diseases | TFAM, HSPA9, HSPD1 | HRH1 3769/4885CACNA1F 2339/4885CHRM2 3091/4885 |
| US-20020010195-A1 | Mitochondria protecting agents for treating mitochondria associated diseases | TFAM, HSPA9, HSPD1 | HRH1 3806/4885CACNA1F 2335/4885CHRM2 3133/4885 |
| US-20020065299-A1 | Mitochondria protecting agents for treating mitochondria associated diseases | TFAM, HSPA9, HSPD1 | HRH1 3720/4885CACNA1F 2333/4885CHRM2 3149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.