Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7048220 | 0.90 | L3MBTL1 (0.53) | RXFP1L3MBTL1HPGDGFERLMNA | |
| SCHEMBL7044700 | 0.82 | SMN1; SMN2 (0.52) | RXFP1NPC1RAB9APOLBL3MBTL1 | |
| SCHEMBL7045001 | 0.81 | SMN1; SMN2 (0.42) | RXFP1NPC1RAB9APOLBL3MBTL1 | |
| SCHEMBL7046457 | 0.80 | ALOX15 (0.48) | RXFP1POLBL3MBTL1HPGDLMNA | |
| SCHEMBL6551997 | 0.79 | PIN1 (0.45) | RXFP1RAB9ATP53LMNAKDM4E | |
| SCHEMBL7044570 | 0.79 | NAAA (0.52) | RXFP1POLBL3MBTL1HPGDTP53 | |
| SCHEMBL7044996 | 0.79 | TRPM8 (0.46) | NPC1RAB9AHPGDLMNAKDM4E | |
| SCHEMBL7044203 | 0.78 | SMN1; SMN2 (0.51) | NPC1RAB9APOLBHPGDTP53 | |
| SCHEMBL6552063 | 0.76 | CNR1 (0.46) | RXFP1POLBTP53LMNAKDM4E | |
| SCHEMBL7042653 | 0.74 | CYP2D6 (0.53) | NPC1RAB9APOLBL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007887-A2 | SUBSTITUTED IMIDAZOLES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-01-30 | — | — | WO | claimed |