SCHEMBL7044244

SCHEMBL7044244

O=S(=O)(O)c1cc(Cl)[c]c(Cl)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.43
FYN P06241 1/20 0.43
ING2 Q9H160 1/20 0.41
TSHR P16473 3/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
LMNA P02545 1/20 0.37
ALDH1A1 P00352 5/20 0.36
NT5E P21589 3/20 0.36
HSD17B10 Q99714 4/20 0.35
TDP1 Q9NUW8 2/20 0.35
CASR P41180 2/20 0.35
CASP6 P55212 3/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
NSD2 O96028 2/20 0.33
GAA P10253 1/20 0.33
PLCG1 P19174 1/20 0.33
DNMT1 P26358 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
PTPN11 Q06124 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10437038 0.87 LCK (0.38) LCKFYNING2TSHRSMN1; SMN2
SCHEMBL5507432 0.85 LCK (0.36) LCKFYNING2TSHRSMN1; SMN2
SCHEMBL1965864 0.75 LMNA (0.38) LMNAALDH1A1
SCHEMBL396496 0.75 CA2 (0.54) LMNATDP1CYP2C9CYP2C19L3MBTL1
SCHEMBL219222 0.74 LCK (0.57) LCKFYNING2TSHRSMN1; SMN2
SCHEMBL197473 0.74 LCK (0.46) LCKFYNING2TSHRSMN1; SMN2
SCHEMBL11409650 0.74 LCK (0.46) LCKFYNING2TSHRSMN1; SMN2
SCHEMBL5505800 0.73 ALDH1A1 (0.39) LCKFYNING2TSHRSMN1; SMN2
SCHEMBL3139602 0.72 CA1 (0.45) LCKFYNING2TSHRSMN1; SMN2
SCHEMBL4304711 0.72 LCK (0.44) LCKFYNING2TSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190154696-A1 Colorimetric Labeling and Detection Methods and Compositions Life Technologies Corporation 2019-05-23 US disclosed
EP-3344782-A1 COLORIMETRIC LABELING AND DETECTION METHODS AND COMPOSITIONS Life Technologies Corporation (US) 2018-07-11 EP disclosed
WO-2017040510-A1 COLORIMETRIC LABELING AND DETECTION METHODS AND COMPOSITIONS Life Technologies Corporation (US) 2017-03-09 WO disclosed
EP-0765965-B1 Process for deying synthetic fibrous polyamid materials DYSTAR TEXTILFARBEN GMBH & CO (DE) 2003-06-04 EP disclosed
WO-2003006560-A2 AQUEOUS INK FORMULATIONS FOR INKJET PRINTING DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2003-01-23 WO disclosed
EP-1127923-A2 Water-soluble fibre-reactive dyestuffs, process for their preparation and their use DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2001-08-29 EP disclosed
EP-0971986-B1 REACTIVE DYES CONTAINING A PERMANENT QUATERNARY AMMONIUM GROUP DYSTAR L P (US) 2001-06-27 EP disclosed
EP-0838504-B1 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof DYSTAR TEXTILFARBEN GMBH & CO (DE) 2000-06-07 EP disclosed
US-6060591-A FOR DYEING A MATERIAL CONTAINING HYDROXY OR CARBOXAMIDE GROUPS OR BOTH DY STAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND K.G. (DE) 2000-05-09 US disclosed
EP-0971986-A1 REACTIVE DYES CONTAINING A PERMANENT QUATERNARY AMMONIUM GROUP DyStar L.P. (US) 2000-01-19 EP disclosed
EP-0838504-A1 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 1998-04-29 EP disclosed
EP-0629667-B1 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof HOECHST AG (DE) 1998-02-25 EP disclosed
EP-0765918-A2 Reactive dye preparations DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 1997-04-02 EP disclosed
EP-0765965-A2 Process for deying synthetic fibrous polyamid materials DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 1997-04-02 EP disclosed
US-5399674-A Dyestuffs containing pyrimidine-carboxylic acid amide radical having fiber-reactive group, processes for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1995-03-21 US disclosed
EP-0629667-A1 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof HOECHST AKTIENGESELLSCHAFT (DE) 1994-12-21 EP disclosed
EP-0624630-A1 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof HOECHST AKTIENGESELLSCHAFT (DE) 1994-11-17 EP disclosed
EP-0603595-A1 Fibre reactive dyes, method for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1994-06-29 EP disclosed
US-5280110-A Fiber-reactive dye HOECHST AKTIENGESELLSCHAFT (DE) 1994-01-18 US disclosed
EP-0548792-A2 Water-soluble reactive dyes, their manufacture and their use HOECHST AKTIENGESELLSCHAFT (DE) 1993-06-30 EP disclosed