Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 5/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 5/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 5/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 5/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 5/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 5/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | HNF4A | P41235 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4085731 | 0.66 | CNR1 (0.60) | CNR1ENPP2 | |
| SCHEMBL7044541 | 0.63 | CNR1 (0.51) | CNR1POLBENPP2 | |
| SCHEMBL4089603 | 0.60 | KDM4E (0.40) | CNR1KDM4EALDH1A1POLBHTT | |
| SCHEMBL4079403 | 0.59 | NAMPT (0.47) | CNR1 | |
| SCHEMBL423397 | 0.58 | LMNA (0.54) | POLBHTTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL28283760 | 0.57 | ALDH1A1 (0.64) | KDM4EALDH1A1POLBHTTTP53 | |
| SCHEMBL28351054 | 0.57 | MMP9 (0.45) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL10572895 | 0.57 | SLC6A2 (0.71) | ALDH1A1HTTTP53CYP1A2CYP3A4 | |
| SCHEMBL6405250 | 0.56 | POLB (0.50) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL12500447 | 0.56 | POLB (0.50) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007887-A2 | SUBSTITUTED IMIDAZOLES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-01-30 | — | — | WO | disclosed |