Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 5/20 | 0.51 |
| ▸ | FAAH | O00519 | 5/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7041230 | 0.83 | NPSR1 (0.44) | CNR1NPSR1POLB | |
| SCHEMBL4085731 | 0.79 | CNR1 (0.60) | CNR1FAAHSMPD1ENPP2 | |
| SCHEMBL4076184 | 0.76 | DGAT1 (0.46) | CNR1NPSR1 | |
| SCHEMBL4089603 | 0.66 | KDM4E (0.40) | CNR1POLBSMPD1 | |
| SCHEMBL27165995 | 0.64 | GAA (0.60) | CNR1POLBENPP2 | |
| SCHEMBL27215736 | 0.64 | GAA (0.49) | CNR1FAAHPOLBENPP2 | |
| SCHEMBL7042641 | 0.63 | DRD2 (0.53) | CNR1NPSR1 | |
| SCHEMBL7044544 | 0.63 | PSEN1 (0.38) | CNR1POLBENPP2 | |
| SCHEMBL4083512 | 0.63 | F11 (0.42) | NPSR1 | |
| SCHEMBL7047749 | 0.63 | ALDH1A1 (0.42) | NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007887-A2 | SUBSTITUTED IMIDAZOLES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-01-30 | — | — | WO | disclosed |