Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 7/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 7/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 7/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 6/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.47 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.36 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17128198 | 0.92 | CHRNB2 (0.50) | CHRNB2CHRNA3CHRNA4CHRNB4CHRNA7 | |
| SCHEMBL2944020 | 0.90 | CHRNB2 (0.39) | CHRNB2CHRNA3CHRNA4CHRNB4CHRNA7 | |
| SCHEMBL1977601 | 0.84 | CHRNB2 (0.52) | CHRNB2CHRNA3CHRNA4CHRNB4CHRNA7 | |
| SCHEMBL23127154 | 0.84 | CHRM1 (0.39) | CHRNB2CHRNA3CHRNA4CHRNB4CHRNA7 | |
| Ammonia Solution, Strong SCHEMBL8195833 | 0.84 | CHRM2 (0.39) | CHRNB2CHRNA3CHRNA4CHRNB4CHRNA7 | |
| SCHEMBL17572218 | 0.84 | CHRM1 (0.39) | CHRNB2CHRNA3CHRNA4CHRNB4CHRNA7 | |
| SCHEMBL2938559 | 0.81 | CHRNB2 (0.41) | CHRNB2CHRNA3CHRNA4CHRNB4CHRNA7 | |
| SCHEMBL14899362 | 0.77 | CHRNB2 (0.40) | CHRNB2CHRNA3CHRNA4CHRNB4CHRNA7 | |
| SCHEMBL4686451 | 0.75 | SLC6A1 (0.34) | CHRNB2CHRNA3CHRNA4CHRNB4CHRNA7 | |
| SCHEMBL21358349 | 0.73 | CHRM1 (0.46) | CHRM1CHRM4HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030195217-A1 | 3,9-Diazabicyclo[3.3.1]nonane derivatives with analgesic activity | IL CENTRO CONSORTILE RICERCHE NEUROPSICOFARMACOLOGICHE A R.L (ABBREVIATED IN NEUROSCINZE S.C.A.R.L.) (IT) | 2003-10-16 | — | — | US | disclosed |
| EP-1259511-A1 | 3,9-DIAZABICYCLO 3.3.1]NONANE DERIVATIVES WITH ANALGESIC ACTIVITY | Il Centro Consortile Ricerche Neuropsicofarmacologiche A R.L. (IT) | 2002-11-27 | — | — | EP | disclosed |
| WO-2001060823-A1 | 3,9-DIAZABICYCLO[3.3.1]NONANE DERIVATIVES WITH ANALGESIC ACTIVITY | IL CENTRO CONSORTILE RICERCHE NEUROPSICOFARMACOLOGICHE A R.L. (IT) | 2001-08-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030195217-A1 | 3,9-Diazabicyclo[3.3.1]nonane derivatives with analgesic activity | OPRD1, OPRK1, OPRM1 | CHRNB2 754/4885CHRNA3 363/4885CHRNA4 877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.