Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 8/20 | 0.61 |
| ▸ | CTSK | P43235 | 6/20 | 0.61 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.55 |
| ▸ | CTSG | P08311 | 4/20 | 0.55 |
| ▸ | CTRB1 | P17538 | 4/20 | 0.55 |
| ▸ | CMA1 | P23946 | 4/20 | 0.55 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4264253 | 0.87 | CTSK (0.61) | CTSSCTSKS1PR3CTSLCTSB | |
| SCHEMBL3645286 | 0.83 | CTSS (0.57) | CTSSCTSKPRSS1CTSGCTRB1 | |
| SCHEMBL7047114 | 0.81 | CTSK (0.55) | CTSSCTSKS1PR3GABRB1GABRB2 | |
| SCHEMBL20470112 | 0.81 | TRPA1 (0.51) | CTSSCTSKPRSS1CTSGCTRB1 | |
| SCHEMBL22506498 | 0.81 | TRPA1 (0.51) | CTSSCTSKPRSS1CTSGCTRB1 | |
| SCHEMBL23200865 | 0.81 | CTSS (0.54) | CTSSCTSKPRSS1CTSGCTRB1 | |
| SCHEMBL5041445 | 0.81 | CTSS (0.71) | CTSSCTSKCTSLCTSB | |
| SCHEMBL5041450 | 0.81 | CTSS (0.71) | CTSSCTSKCTSLCTSB | |
| SCHEMBL12849606 | 0.80 | TRPA1 (0.50) | CTSSCTSKPRSS1CTSGCTRB1 | |
| SCHEMBL14448525 | 0.80 | CTSS (0.53) | CTSSCTSKPRSS1CTSGCTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030083503-A1 | Synthesis of acylated keto amides from sulfonyl amides | FRANTZ DOUG E (US) | 2003-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030083503-A1 | Synthesis of acylated keto amides from sulfonyl amides | AADAC, ACAA2, ACSS2 | CTSS 1044/4885CTSK 1459/4885PRSS1 2026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.