Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.61 |
| ▸ | CTSS | P25774 | 3/20 | 0.61 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 3/20 | 0.46 |
| ▸ | PPARA | Q07869 | 3/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24645190 | 0.90 | S1PR3 (0.53) | CTSKCTSSGABRB1GABRB2PPARG | |
| SCHEMBL7047114 | 0.90 | CTSK (0.55) | CTSKCTSSGABRB1GABRB2PPARG | |
| SCHEMBL7044030 | 0.87 | CTSS (0.52) | CTSKCTSSS1PR3ALDH1A1CYP3A4 | |
| SCHEMBL7045324 | 0.87 | CTSS (0.61) | CTSKCTSSGABRB1GABRB2S1PR3 | |
| SCHEMBL7048516 | 0.86 | CTSS (0.54) | CTSKCTSSGABRB1GABRB2S1PR3 | |
| SCHEMBL264362 | 0.86 | CTSK (0.66) | CTSKCTSSGABRB1GABRB2PPARG | |
| SCHEMBL525862 | 0.86 | CTSK (0.66) | CTSKCTSSGABRB1GABRB2PPARG | |
| SCHEMBL116386 | 0.86 | CTSK (0.66) | CTSKCTSSGABRB1GABRB2PPARG | |
| SCHEMBL16171655 | 0.86 | CTSK (0.66) | CTSKCTSSGABRB1GABRB2PPARG | |
| SCHEMBL16174111 | 0.86 | CTSK (0.66) | CTSKCTSSGABRB1GABRB2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117247337-A | Method for asymmetrically synthesizing 1, 2-trans-amino alcohol and derivative thereof | 凯特立斯（深圳）科技有限公司 | 2023-12-19 | — | — | CN | disclosed |
| US-20090012061-A1 | A Method of Treating Cancer | MERCK SHARP & DOHME CORP. | 2009-01-08 | — | — | US | disclosed |
| EP-1791969-A4 | A METHOD OF TREATING CANCER | MERCK & CO INC (US) | 2008-07-02 | — | — | EP | disclosed |
| EP-1791969-A2 | A METHOD OF TREATING CANCER | Merck & Co., Inc. (US) | 2007-06-06 | — | — | EP | disclosed |
| WO-2006031607-A2 | A METHOD OF TREATING CANCER | MERCK & CO., INC. (US) | 2006-03-23 | — | — | WO | disclosed |
| US-20030083503-A1 | Synthesis of acylated keto amides from sulfonyl amides | FRANTZ DOUG E (US) | 2003-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012061-A1 | A Method of Treating Cancer | KIF5B, MKI67, KIF2C | CTSK 877/4885CTSS 1446/4885GABRB1 4055/4885 |
| US-20030083503-A1 | Synthesis of acylated keto amides from sulfonyl amides | AADAC, ACAA2, ACSS2 | CTSK 1459/4885CTSS 1044/4885GABRB1 1299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.