Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ORAI1 | Q96D31 | 3/20 | 0.41 |
| ▸ | ORAI2 | Q96SN7 | 3/20 | 0.41 |
| ▸ | ORAI3 | Q9BRQ5 | 3/20 | 0.41 |
| ▸ | TRPV6 | Q9H1D0 | 3/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.32 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.32 |
| ▸ | ITGAL | P20701 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromobenzene SCHEMBL27149738 | 1.00 | ALDH1A1 (0.58) | ALDH1A1TDP1MAPK1ORAI1ORAI2 | |
| Bromobenzene SCHEMBL3834436 | 0.95 | ALDH1A1 (0.58) | ALDH1A1TDP1MAPK1ORAI1ORAI2 | |
| Bromobenzene SCHEMBL14795351 | 0.84 | ALDH1A1 (0.58) | ALDH1A1TDP1MAPK1ORAI1ORAI2 | |
| Bromobenzene SCHEMBL6115841 | 0.84 | ALDH1A1 (0.41) | ALDH1A1TDP1MAPK1SMN1; SMN2CYP2C19 | |
| Bromobenzene SCHEMBL129999 | 0.82 | ALDH1A1 (0.55) | ALDH1A1TDP1MAPK1ORAI1ORAI2 | |
| Bromobenzene SCHEMBL28753154 | 0.80 | ALDH1A1 (0.79) | ALDH1A1TDP1MAPK1CYP2A6NPC1 | |
| Bromobenzene SCHEMBL1736835 | 0.80 | ALDH1A1 (0.92) | ALDH1A1TDP1MAPK1ORAI1ORAI2 | |
| Bromobenzene SCHEMBL313507 | 0.80 | ALDH1A1 (0.92) | ALDH1A1TDP1MAPK1ORAI1ORAI2 | |
| Bromobenzene SCHEMBL29116318 | 0.80 | ALDH1A1 (0.92) | ALDH1A1TDP1MAPK1ORAI1ORAI2 | |
| Bromobenzene SCHEMBL313505 | 0.80 | ALDH1A1 (0.92) | ALDH1A1TDP1MAPK1ORAI1ORAI2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100256378-A1 | FLUORESCENT CELLULAR MARKERS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-10-07 | — | — | US | claimed |
| EP-3091014-A1 | FLUORESCENT CELLULAR MARKERS | Zayas, Beatriz (US) | 2016-11-09 | — | — | EP | disclosed |
| US-8124770-B2 | Fluorescent cellular markers | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-02-28 | — | — | US | disclosed |
| US-20100256378-A1 | FLUORESCENT CELLULAR MARKERS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256378-A1 | FLUORESCENT CELLULAR MARKERS | AIFM1, CASP3, BAX | ALDH1A1 3502/4885TDP1 1492/4885MAPK1 3253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.