Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HTR4 | Q13639 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6746510 | 0.99 | P2RX7 (0.48) | P2RX7KMT2ANPC1HTR4MEN1 | |
| SCHEMBL7046082 | 0.98 | P2RX7 (0.44) | P2RX7KMT2ANPC1HTR4CNR1 | |
| SCHEMBL7044448 | 0.95 | HTR4 (0.41) | P2RX7HTR4 | |
| SCHEMBL4610877 | 0.76 | KMT2A (0.51) | KMT2ANPC1MEN1KDM4ESMN1; SMN2 | |
| SCHEMBL7046661 | 0.76 | P2RX7 (0.49) | P2RX7KMT2AHTR4MEN1 | |
| SCHEMBL7959599 | 0.75 | P2RX7 (0.51) | P2RX7KMT2ANPC1HTR4MEN1 | |
| SCHEMBL6746518 | 0.75 | P2RX7 (0.51) | P2RX7KMT2ANPC1HTR4MEN1 | |
| SCHEMBL7044113 | 0.75 | ALDH1A1 (0.52) | KMT2ANPC1MEN1KDM4ESMN1; SMN2 | |
| SCHEMBL4613206 | 0.75 | MEN1 (0.41) | KMT2AMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL4612617 | 0.74 | MEN1 (0.52) | KMT2ANPC1MEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1460064-A1 | Indole-2-carboxamide derivatives useful as beta-2 agonists | Pfizer Limited (GB) | 2004-09-22 | — | — | EP | claimed |
| EP-1460064-A1 | Indole-2-carboxamide derivatives useful as beta-2 agonists | Pfizer Limited (GB) | 2004-09-22 | — | — | EP | disclosed |