Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 9/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7501445 | 0.80 | TRPA1 (0.33) | — | |
| SCHEMBL5315866 | 0.78 | SLC6A4 (0.41) | — | |
| SCHEMBL5312303 | 0.78 | SLC6A4 (0.41) | — | |
| SCHEMBL5315862 | 0.78 | SLC6A4 (0.41) | — | |
| SCHEMBL5312299 | 0.78 | SLC6A4 (0.41) | — | |
| SCHEMBL5312306 | 0.78 | SLC6A4 (0.41) | — | |
| SCHEMBL8756087 | 0.77 | EPHX1 (0.33) | EPHX1EPHX2 | |
| SCHEMBL28290538 | 0.75 | CYP1A2 (0.34) | EPHX1EPHX2 | |
| SCHEMBL28217865 | 0.75 | CYP1A2 (0.38) | EPHX1EPHX2 | |
| SCHEMBL8063149 | 0.75 | TDP1 (0.35) | EPHX1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040054209-A1 | Synthesis of (±)-2-((dimethylamino)methyl)-1-(aryl)cyclohexanols | PURDUE PHARMA L.P. | 2004-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040054209-A1 | Synthesis of (±)-2-((dimethylamino)methyl)-1-(aryl)cyclohexanols | BHMT2, METTL3, PNMT | SIRT2 1074/4885EPHX1 4140/4885EPHX2 2475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.