Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PGK1 | P00558 | 1/20 | 0.36 |
| ▸ | PGK2 | P07205 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6045256 | 0.85 | PPARD (0.50) | PPARDPOLBPGK1PGK2 | |
| SCHEMBL1486664 | 0.84 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1POLBKMT2ACALM1 | |
| SCHEMBL915209 | 0.83 | PPARD (0.37) | PPARDALDH1A1POLBKDM4EGAA | |
| SCHEMBL28437720 | 0.83 | MMP13 (0.48) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL914509 | 0.82 | ANPEP (0.44) | PPARDSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL5798610 | 0.81 | PGK1 (0.55) | ALDH1A1AKR1B1CALM1KDM4EGAA | |
| SCHEMBL915542 | 0.80 | PPARD (0.44) | PPARDALDH1A1POLBPGK1PGK2 | |
| SCHEMBL1976119 | 0.79 | KMT2A (0.34) | SMN1; SMN2ALDH1A1POLBKMT2AAKR1B1 | |
| SCHEMBL6028463 | 0.78 | PPARD (0.44) | PPARDPOLBPTGS2PGK1PGK2 | |
| SCHEMBL9927129 | 0.77 | DAO (0.42) | PPARDSMN1; SMN2PTGS2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003018013-A1 | STILBENE DERIVATIVE HAVING CYTOCHROME P450 1B1 INHIBITORY ACTIVITY, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, METHOD FOR PREPARING THE SAME, AND COMPOSITION INCLUDING THE SAME | PROMEDITECH, INC. (KR) | 2003-03-06 | — | — | WO | disclosed |