Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.34 |
| ▸ | CDK9 | P50750 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1486664 | 0.89 | ALDH1A1 (0.41) | MAPTHTTCCNT1CDK9TSHR | |
| SCHEMBL25614635 | 0.84 | PTGS2 (0.50) | MAPTHTTEGFRPTGS2 | |
| SCHEMBL11949136 | 0.81 | MAPT (0.35) | MAPTHTTCCNT1CDK9TSHR | |
| SCHEMBL13913134 | 0.81 | TSHR (0.50) | PPARDMAPTHTTCCNT1CDK9 | |
| SCHEMBL1621101 | 0.77 | DAO (0.53) | DAOMAPTGRIN2DGRIN3BGRIN1 | |
| SCHEMBL7046484 | 0.77 | PPARD (0.41) | PPARDSMN1; SMN2PTGS2L3MBTL1 | |
| SCHEMBL30279733 | 0.76 | CYP19A1 (0.36) | PPARDMAPTCCNT1CDK9 | |
| SCHEMBL25612287 | 0.76 | CYP19A1 (0.36) | PPARDMAPTCCNT1CDK9 | |
| SCHEMBL3396258 | 0.76 | EGFR (0.43) | PPARDMAPTHTTTSHREGFR | |
| SCHEMBL9512480 | 0.76 | PPARD (0.45) | PPARDMAPTHTTCCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149663-A1 | BORONIC ACID COMPOSITIONS AND METHODS RELATED TO CANCER | GEORGETOWN UNIVERSITY (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149663-A1 | BORONIC ACID COMPOSITIONS AND METHODS RELATED TO CANCER | RB1, RBBP5, CCNB1 | DAO 4617/4885PPARD 3013/4885MAPT 4265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.