Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHEB | Q15382 | 2/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | BRS3 | P32247 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6552425 | 0.85 | LTB4R (0.57) | KDM4CLTB4RKDM4EALDH1A1 | |
| SCHEMBL6551997 | 0.84 | PIN1 (0.45) | LTB4RKDM4ERAB9ASMN1; SMN2LMNA | |
| SCHEMBL7042642 | 0.81 | ALOX5 (0.57) | LTB4RPOLBALDH1A1 | |
| SCHEMBL7046586 | 0.79 | MAPT (0.40) | NPC1POLBRAB9ASMN1; SMN2LMNA | |
| SCHEMBL7042512 | 0.76 | CNR1 (0.58) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7043397 | 0.76 | CNR1 (0.58) | NPC1POLBRAB9ASMN1; SMN2LMNA | |
| SCHEMBL7046457 | 0.75 | ALOX15 (0.48) | POLBLMNA | |
| SCHEMBL6553452 | 0.70 | TDP1 (0.50) | LTB4RNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL7044623 | 0.70 | NPC1 (0.43) | LTB4RNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL25463459 | 0.69 | DAO (0.41) | KDM4CLMNAALDH1A1PTGDR2DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007887-A2 | SUBSTITUTED IMIDAZOLES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-01-30 | — | — | WO | disclosed |