Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7042373 | 0.82 | ALDH1A1 (0.44) | ALDH1A1KDM4EGAAMAPTSMN1; SMN2 | |
| SCHEMBL7042377 | 0.79 | CA2 (0.39) | ALDH1A1KDM4EGAAMAPTSMN1; SMN2 | |
| SCHEMBL12504651 | 0.79 | SCN4A (0.44) | SCN4AALDH1A1FFAR4MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL15561625 | 0.78 | GAA (0.34) | ALDH1A1KDM4EGAAMAPTSMN1; SMN2 | |
| SCHEMBL13648047 | 0.75 | GAA (0.38) | SCN4AALDH1A1KDM4EGAAMAPT | |
| SCHEMBL7045444 | 0.74 | CYP3A4 (0.45) | SCN4AALDH1A1GAAFFAR4MAPT | |
| SCHEMBL7040066 | 0.73 | CYP3A4 (0.40) | ALDH1A1KDM4EGAAMAPTSMN1; SMN2 | |
| SCHEMBL10510118 | 0.73 | MAPT (0.50) | SCN4AALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL8946556 | 0.72 | ALDH1A1 (0.37) | ALDH1A1KDM4EGAAMAPTSMN1; SMN2 | |
| SCHEMBL14189350 | 0.71 | ACHE (0.50) | SCN4AALDH1A1KDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613786-B2 | Treating urinary incontinence, asthma, irritable bowel syndrome or male erectile dysfunction | BRISTOL-MYERS SQUIBB COMPANY | 2003-09-02 | — | — | US | disclosed |
| US-20030144333-A1 | Thiophenyl triazol-3-one derivatives as smooth muscle relaxants | HEWAWASAM PIYASENA (US) | 2003-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144333-A1 | Thiophenyl triazol-3-one derivatives as smooth muscle relaxants | PDE3A, ADRB2, ADRB3 | SCN4A 791/4885ALDH1A1 1237/4885KDM4E 1943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.