Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | AGXT | P21549 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8946911 | 0.98 | ALDH1A1 (0.36) | ALDH1A1NQO2POLBRAB9AAGXT | |
| SCHEMBL10763176 | 0.75 | — | — | |
| SCHEMBL148267 | 0.72 | ALDH1A1 (0.43) | ALDH1A1NQO2POLBRAB9AAGXT | |
| SCHEMBL7046840 | 0.72 | SCN4A (0.39) | ALDH1A1NQO2KDM4ELMNAMEN1 | |
| SCHEMBL3008135 | 0.71 | IMPDH2 (0.41) | ALDH1A1POLBAGXTACHEGAA | |
| SCHEMBL1635426 | 0.70 | ACHE (0.50) | ALDH1A1NQO2POLBMEN1MAPT | |
| SCHEMBL12326160 | 0.70 | ALDH1A1 (0.42) | ALDH1A1POLBRAB9AAGXTLMNA | |
| SCHEMBL29793476 | 0.70 | ACHE (0.50) | ALDH1A1NQO2POLBMEN1MAPT | |
| Hydrochloric Acid SCHEMBL9526742 | 0.70 | ALDH1A1 (0.47) | ALDH1A1KDM4ELMNAMEN1MAPT | |
| Hydrochloric Acid SCHEMBL8946544 | 0.70 | IMPDH2 (0.40) | ALDH1A1POLBAGXTMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516788-A | TREATMENT OF ATHEROSCLEROSIS; ANTIISCHEMIC, ANTICARCINOGENIC AGENTS; ANTICOAGULANTS | UNIVERSITY OF BATH (GB) | 1996-05-14 | — | — | US | disclosed |
| EP-0481708-A1 | Indenoindole compounds | UNIVERSITY OF BATH (GB) | 1992-04-22 | — | — | EP | disclosed |