Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | F11 | P03951 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NR1I3 | Q14994 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4083512 | 0.84 | F11 (0.42) | ALDH1A1NPSR1MAPTF11TP53 | |
| SCHEMBL7041230 | 0.79 | NPSR1 (0.44) | ALDH1A1NPSR1F11USP2CYP1A2 | |
| SCHEMBL4076184 | 0.77 | DGAT1 (0.46) | NPSR1MAPTF11CYP1A2CYP3A4 | |
| SCHEMBL7042641 | 0.69 | DRD2 (0.53) | ALDH1A1NPSR1NR1I3NR1I2 | |
| SCHEMBL2846531 | 0.69 | FAAH (0.43) | F11HPGDCYP3A4CYP2C19MEN1 | |
| SCHEMBL1927930 | 0.69 | CFTR (0.48) | ALDH1A1NPSR1HPGDTP53USP2 | |
| SCHEMBL9525207 | 0.68 | MAPK14 (0.43) | ALDH1A1F11 | |
| SCHEMBL9370452 | 0.68 | FAAH (0.41) | ALDH1A1F11 | |
| SCHEMBL4069849 | 0.68 | F11 (0.39) | ALDH1A1NPSR1MAPTF11HPGD | |
| SCHEMBL29460875 | 0.67 | TSHR (0.56) | ALDH1A1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007887-A2 | SUBSTITUTED IMIDAZOLES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-01-30 | — | — | WO | disclosed |