Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.67 |
| ▸ | CA2 | P00918 | 16/20 | 0.67 |
| ▸ | CA1 | P00915 | 15/20 | 0.67 |
| ▸ | CA9 | Q16790 | 5/20 | 0.51 |
| ▸ | CA12 | O43570 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6226263 | 0.87 | CA1 (0.75) | CA2CA1CA9CA12 | |
| SCHEMBL6866220 | 0.84 | CA2 (0.54) | PTGESCA2CA1CA9CA12 | |
| SCHEMBL6867142 | 0.82 | CA2 (0.52) | PTGESCA2CA1CA9CA12 | |
| SCHEMBL7049852 | 0.82 | PTGES (0.58) | PTGESCA2CA1 | |
| SCHEMBL976823 | 0.81 | PTGES (1.00) | PTGESCA2CA1CA9CA12 | |
| SCHEMBL7052354 | 0.80 | PTGES (0.56) | PTGESCA2CA1 | |
| SCHEMBL1083553 | 0.80 | HDAC1 (0.73) | — | |
| SCHEMBL7076342 | 0.78 | PTGES (0.60) | PTGESCA2CA1 | |
| SCHEMBL11698871 | 0.78 | CA2 (0.71) | CA2CA1CA9CA12 | |
| SCHEMBL7052309 | 0.77 | PTGES (0.56) | PTGESCA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030191323-A1 | Hypoglycemic agent | AJINOMOTO CO., INC. (JP) | 2003-10-09 | — | — | US | disclosed |
| US-20030162818-A1 | Acylsulfonamide derivative | AJINOMOTO CO. INC. (JP) | 2003-08-28 | — | — | US | disclosed |
| US-6555584-B1 | Acetyl-coa carboxylase inhibitors | AJINOMOTO CO., INC. (JP) | 2003-04-29 | — | — | US | disclosed |
| EP-1300142-A1 | HYPOGLYCEMICS | Ajinomoto Co., Inc. (JP) | 2003-04-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162818-A1 | Acylsulfonamide derivative | ACSS2, ACACA, FASN | PTGES 3406/4885CA2 2304/4885CA1 2192/4885 |
| US-20030191323-A1 | Hypoglycemic agent | GPR119, IAPP, SLC5A2 | PTGES 2159/4885CA2 831/4885CA1 2426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.