Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 2/20 | 0.52 |
| ▸ | METAP1 | P53582 | 2/20 | 0.52 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LAP3 | P28838 | 3/20 | 0.41 |
| ▸ | ANPEP | P15144 | 3/20 | 0.41 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.41 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7334290 | 0.91 | CSNK1E (0.49) | METAP2METAP1CSNK1ELAP3ANPEP | |
| SCHEMBL7050427 | 0.85 | SIGMAR1 (0.43) | METAP2METAP1CSNK1ELAP3ANPEP | |
| SCHEMBL7052637 | 0.85 | METAP2 (0.46) | METAP2METAP1CSNK1EANPEPERAP1 | |
| SCHEMBL7092250 | 0.80 | EPHX1 (0.58) | CSNK1ELAP3ANPEPSLC6A2TAAR1 | |
| SCHEMBL7092247 | 0.80 | EPHX1 (0.58) | CSNK1ELAP3ANPEPSLC6A2TAAR1 | |
| Hydrochloric Acid SCHEMBL8535481 | 0.78 | METAP2 (0.53) | METAP2METAP1TDP1ANPEPTAAR1 | |
| SCHEMBL7054865 | 0.78 | TAAR1 (0.43) | METAP2METAP1CSNK1ELAP3ANPEP | |
| SCHEMBL7342879 | 0.78 | TACR1 (0.53) | CSNK1ELAP3ANPEPRNPEPDNPEP | |
| SCHEMBL18063343 | 0.77 | TDP1 (0.51) | METAP2METAP1MMP8TDP1L3MBTL1 | |
| SCHEMBL7051572 | 0.77 | TAAR1 (0.46) | METAP2METAP1CSNK1ESLC6A2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004502669-A | — | — | 2004-01-29 | — | — | JP | claimed |
| EP-1353898-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002002512-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |