Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 2/20 | 0.39 |
| ▸ | METAP1 | P53582 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | LAP3 | P28838 | 4/20 | 0.37 |
| ▸ | ANPEP | P15144 | 3/20 | 0.37 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.37 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7052637 | 0.87 | METAP2 (0.46) | CSNK1EKMT2ASLC15A1METAP2METAP1 | |
| SCHEMBL7051572 | 0.81 | TAAR1 (0.46) | TAAR1CSNK1ESLC15A1IDO1METAP2 | |
| SCHEMBL7340739 | 0.79 | EPHX1 (0.47) | TAAR1CSNK1ESLC15A1ALDH1A1EPHX1 | |
| SCHEMBL7092247 | 0.79 | EPHX1 (0.58) | TAAR1CSNK1ESLC15A1MAPK1EPHX1 | |
| SCHEMBL7092250 | 0.79 | EPHX1 (0.58) | TAAR1CSNK1ESLC15A1MAPK1EPHX1 | |
| SCHEMBL7050427 | 0.78 | SIGMAR1 (0.43) | CSNK1EKMT2ASLC15A1METAP2METAP1 | |
| SCHEMBL7047857 | 0.78 | METAP2 (0.52) | TAAR1CSNK1ESLC15A1METAP2METAP1 | |
| SCHEMBL7050872 | 0.75 | IDO1 (0.50) | TAAR1CSNK1EKMT2AIDO1TDO2 | |
| SCHEMBL3349203 | 0.75 | MPO (0.46) | TAAR1CSNK1EKMT2AANPEPERAP2 | |
| SCHEMBL7156004 | 0.75 | METAP2 (0.57) | KMT2AMETAP2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004502669-A | — | — | 2004-01-29 | — | — | JP | claimed |
| EP-1353898-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002002512-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |