Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | METAP1 | P53582 | 1/20 | 0.46 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.42 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 2/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.41 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | MC3R | P41968 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7340739 | 0.91 | EPHX1 (0.47) | CSNK1EANPEPSLC15A1ALDH1A1PPARG | |
| SCHEMBL7054865 | 0.87 | TAAR1 (0.43) | METAP2METAP1CSNK1EANPEPERAP1 | |
| SCHEMBL7051572 | 0.85 | TAAR1 (0.46) | METAP2METAP1CSNK1ESLC15A1PPARG | |
| SCHEMBL7047857 | 0.85 | METAP2 (0.52) | METAP2METAP1CSNK1EANPEPERAP1 | |
| SCHEMBL7050427 | 0.85 | SIGMAR1 (0.43) | METAP2METAP1CSNK1EANPEPERAP1 | |
| SCHEMBL7092250 | 0.80 | EPHX1 (0.58) | CSNK1EANPEPSLC15A1KDM4ETRPA1 | |
| SCHEMBL7092247 | 0.80 | EPHX1 (0.58) | CSNK1EANPEPSLC15A1KDM4ETRPA1 | |
| Hydrochloric Acid SCHEMBL8535481 | 0.78 | METAP2 (0.53) | METAP2METAP1ANPEPERAP1ERAP2 | |
| SCHEMBL7050872 | 0.77 | IDO1 (0.50) | METAP2CSNK1EMEN1KMT2AALDH1A1 | |
| SCHEMBL6445044 | 0.76 | EPHX1 (0.58) | CSNK1EANPEPSLC15A1KDM4ETRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004502669-A | — | — | 2004-01-29 | — | — | JP | claimed |
| EP-1353898-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002002512-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |