Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7159796 | 0.83 | TAAR1 (0.52) | HTR2ATAAR1AOC3 | |
| SCHEMBL3350055 | 0.80 | CAPN1 (0.50) | CAPN1HTR2AADRA1ATAAR1MEN1 | |
| SCHEMBL8989272 | 0.78 | ADRA1A (0.63) | HTR2AADRA1ATAAR1AOC3HSD17B10 | |
| SCHEMBL7054865 | 0.74 | TAAR1 (0.43) | TAAR1AOC3KMT2A | |
| SCHEMBL7048497 | 0.74 | CAPN1 (0.48) | CAPN1HTR2AADRA1ATAAR1AOC3 | |
| SCHEMBL3659272 | 0.73 | HSD17B10 (0.57) | HTR2AADRA1ATAAR1AOC3HSD17B10 | |
| SCHEMBL3659269 | 0.73 | HSD17B10 (0.57) | HTR2AADRA1ATAAR1AOC3HSD17B10 | |
| SCHEMBL5664114 | 0.72 | MTNR1B (0.58) | HTR2AADRA1ATAAR1MTNR1AMTNR1B | |
| SCHEMBL11488471 | 0.72 | HTR2A (0.56) | CAPN1HTR2AADRA1ATAAR1HSD17B10 | |
| SCHEMBL3660479 | 0.71 | HSD17B10 (0.62) | HTR2AADRA1ATAAR1AOC3HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004502669-A | — | — | 2004-01-29 | — | — | JP | claimed |
| EP-1353898-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002002512-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |