Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.52 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | METAP1 | P53582 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | AGXT | P21549 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7048503 | 0.83 | CAPN1 (0.51) | TAAR1AOC3HTR2A | |
| SCHEMBL7051572 | 0.80 | TAAR1 (0.46) | TAAR1METAP2METAP1IDO1AGXT | |
| SCHEMBL7050872 | 0.80 | IDO1 (0.50) | TAAR1AOC3METAP2IDO1 | |
| SCHEMBL3353932 | 0.78 | BCHE (0.52) | TAAR1SLC2A1CHRM2CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL5225498 | 0.77 | BCHE (0.51) | TAAR1SLC2A1CHRM2CHRM1CHRM3 | |
| SCHEMBL5246588 | 0.76 | TAAR1 (0.69) | TAAR1SLC2A1CYP2D6IDO1AGXT | |
| SCHEMBL7047857 | 0.76 | METAP2 (0.52) | TAAR1METAP2METAP1 | |
| SCHEMBL7713131 | 0.76 | TAAR1 (0.57) | TAAR1AOC3ABCB1HTR1ADRD2 | |
| SCHEMBL30849685 | 0.76 | TAAR1 (0.53) | TAAR1AOC3ABCB1HTR1ADRD2 | |
| SCHEMBL7710830 | 0.76 | TAAR1 (0.53) | TAAR1AOC3ABCB1HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004502669-A | — | — | 2004-01-29 | — | — | JP | claimed |
| EP-1353898-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002002512-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |