Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MPI | P34949 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4339179 | 0.87 | ALOX5 (0.47) | IDO1GAAKDM4EALDH1A1MPI | |
| SCHEMBL12761250 | 0.86 | GP6 (0.37) | IDO1GAAKDM4EALDH1A1MPI | |
| SCHEMBL4344106 | 0.82 | FYN (0.43) | IDO1NOTUMNPC1TP53TSHR | |
| SCHEMBL2288755 | 0.81 | KMO (0.49) | IDO1GAAKDM4EALDH1A1MPI | |
| SCHEMBL4341054 | 0.81 | PIK3CA (0.44) | IDO1GAAKDM4EALDH1A1MPI | |
| SCHEMBL705727 | 0.80 | ALDH1A1 (0.42) | IDO1ALDH1A1GFERTSHRRAB9A | |
| SCHEMBL2406795 | 0.80 | MEN1 (0.46) | IDO1KDM4EALDH1A1NPC1TP53 | |
| SCHEMBL4655029 | 0.79 | GP6 (0.49) | GAAKDM4EALDH1A1NPC1JAK2 | |
| SCHEMBL16174510 | 0.79 | IDO1 (0.37) | IDO1GAAALDH1A1NOTUMSMN1; SMN2 | |
| SCHEMBL16855883 | 0.78 | MAPK13 (0.44) | KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9724673-B2 | Supported alkoxylated organotin reactant, preparation and use for heterogeneous-phase synthesis of tetrazoles | UNIVERSITE DE NANTES (FR) | 2017-08-08 | — | — | US | claimed |
| EP-2726515-B1 | SUPPORTED ALKOXYLATED ORGANOTIN REACTANT, PREPARATION AND USE FOR HETEROGENEOUS-PHASE SYNTHESIS OF TETRAZOLES | CENTRE NAT RECH SCIENT (FR) | 2015-04-01 | — | — | EP | claimed |
| US-20140206825-A1 | SUPPORTED ALKOXYLATED ORGANOTIN REACTANT, PREPARATION AND USE FOR HETEROGENEOUS-PHASE SYNTHESIS OF TETRAZOLES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2014-07-24 | — | — | US | claimed |
| EP-2726515-A1 | SUPPORTED ALKOXYLATED ORGANOTIN REACTANT, PREPARATION AND USE FOR HETEROGENEOUS-PHASE SYNTHESIS OF TETRAZOLES | Centre National De La Recherche Scientifique (FR) | 2014-05-07 | — | — | EP | claimed |
| WO-2013001235-A1 | SUPPORTED ALKOXYLATED ORGANOTIN REACTANT, PREPARATION AND USE FOR HETEROGENEOUS-PHASE SYNTHESIS OF TETRAZOLES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2013-01-03 | — | — | WO | claimed |
| CN-114306604-A | Use of farnesyl transferase inhibitors for the treatment of cancer | 库拉肿瘤学公司 | 2022-04-12 | — | — | CN | disclosed |
| EP-3976190-A1 | NEW ENDOPEROXIDE COMPOUNDS, PROCESS FOR OBTAINING THEM AND USES THEREOF FOR CONTROL OF PERKINSIOSIS IN BIVALVES | CCMAR - Centro de Ciências Do Mar Universidade Do Algarve (PT) | 2022-04-06 | — | — | EP | disclosed |
| CN-114107497-A | Use of farnesyl transferase inhibitors for the treatment of cancer | 库拉肿瘤学公司 | 2022-03-01 | — | — | CN | disclosed |
| WO-2020240266-A1 | NEW ENDOPEROXIDE COMPOUNDS, PROCESS FOR OBTAINING THEM AND USES THEREOF FOR CONTROL OF PERKINSIOSIS IN BIVALVES | CCMAR - CENTRO DE CIÊNCIAS DO MAR UNIVERSIDADE DO ALGARVE (PT) | 2020-12-03 | — | — | WO | disclosed |
| US-9724673-B2 | Supported alkoxylated organotin reactant, preparation and use for heterogeneous-phase synthesis of tetrazoles | UNIVERSITE DE NANTES (FR) | 2017-08-08 | — | — | US | disclosed |
| US-9724673-B2 | Supported alkoxylated organotin reactant, preparation and use for heterogeneous-phase synthesis of tetrazoles | UNIVERSITE DE NANTES (FR) | 2017-08-08 | — | — | US | disclosed |
| US-9724673-B2 | Supported alkoxylated organotin reactant, preparation and use for heterogeneous-phase synthesis of tetrazoles | UNIVERSITE DE NANTES (FR) | 2017-08-08 | — | — | US | disclosed |
| EP-0230270-B1 | FUSED BENZAZEPINES | SCHERING CORPORATION (US) | 1990-08-01 | — | — | EP | disclosed |
| EP-0254737-B1 | FUSED BENZAZEPINES | SCHERING CORPORATION (US) | 1990-07-25 | — | — | EP | disclosed |
| US-4925777-A | Direct positives | FUJI PHOTO FILM CO., LTD. (JP) | 1990-05-15 | — | — | US | disclosed |
| EP-0254737-A1 | FUSED BENZAZEPINES. | SCHERING CORP (US) | 1988-02-03 | — | — | EP | disclosed |
| EP-0230270-A2 | Fused benzazepines | SCHERING CORPORATION (US) | 1987-07-29 | — | — | EP | disclosed |
| US-4647572-A | Iodoallyl and iodopropargyl substituted tetrazoles and anti-microbial compositions thereof | MEIJI SEIKA KAISHA, LTD. (JP) | 1987-03-03 | — | — | US | disclosed |
| EP-0107859-A1 | Tetrazole compounds, process for preparing the same and antibacterial and antifungal compositions containing the same as active ingredient | MEIJI SEIKA KAISHA LTD. (JP) | 1984-05-09 | — | — | EP | disclosed |
| EP-0028717-A1 | 6,7-Benzomorphan derivatives, processes for their production, pharmaceutical compositions containing said derivatives and their use as pharmaceuticals | ACF CHEMIEFARMA NV (NL) | 1981-05-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140206825-A1 | SUPPORTED ALKOXYLATED ORGANOTIN REACTANT, PREPARATION AND USE FOR HETEROGENEOUS-PHASE SYNTHESIS OF TETRAZOLES | ALK, TST, TEKT1 | IDO1 950/4885GAA 3403/4885KDM4E 3246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.