Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 10/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | TACR2 | P21452 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SHBG | P04278 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19357607 | 0.98 | PTGS2 (0.53) | PTGS2CYP3A4GPR84KCNH2ESR1 | |
| SCHEMBL30727511 | 0.98 | PTGS2 (0.53) | PTGS2CYP3A4GPR84KCNH2ESR1 | |
| SCHEMBL22738178 | 0.81 | BACE1 (0.35) | ACHE | |
| SCHEMBL8414491 | 0.80 | PTGS2 (0.50) | PTGS2CYP3A4GPR84KCNH2ESR1 | |
| SCHEMBL8523463 | 0.78 | HRH2 (0.47) | PTGS2CYP3A4GPR84KCNH2 | |
| SCHEMBL8944425 | 0.78 | GPR84 (0.45) | PTGS2CYP3A4GPR84KCNH2ESR1 | |
| SCHEMBL31287855 | 0.78 | ALOX5 (0.49) | PTGS2CYP3A4GPR84KCNH2 | |
| SCHEMBL31287819 | 0.78 | PTGS2 (0.51) | PTGS2GPR84KCNH2 | |
| SCHEMBL9662963 | 0.77 | NOS3 (0.39) | PTGS2CYP3A4GPR84ESR1ALDH1A1 | |
| SCHEMBL23880689 | 0.77 | CDK1 (0.48) | PTGS2GPR84KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8476439-B2 | Pyridine classical cannabinoid compounds and related methods of use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2013-07-02 | — | — | US | disclosed |
| US-8476439-B2 | Pyridine classical cannabinoid compounds and related methods of use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2013-07-02 | — | — | US | disclosed |
| US-8476439-B2 | Pyridine classical cannabinoid compounds and related methods of use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2013-07-02 | — | — | US | disclosed |
| US-8431595-B2 | Furanopyridine cannabinoid compounds and related methods of use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2013-04-30 | — | — | US | disclosed |
| US-8431595-B2 | Furanopyridine cannabinoid compounds and related methods of use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2013-04-30 | — | — | US | disclosed |
| US-8431595-B2 | Furanopyridine cannabinoid compounds and related methods of use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2013-04-30 | — | — | US | disclosed |
| US-20120220773-A1 | PYRIDINE CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2012-08-30 | — | — | US | disclosed |
| US-20120220773-A1 | PYRIDINE CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2012-08-30 | — | — | US | disclosed |
| US-20120220773-A1 | PYRIDINE CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2012-08-30 | — | — | US | disclosed |
| US-8124771-B2 | Pyridine classical cannabinoid compounds and related methods of use | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2012-02-28 | — | — | US | disclosed |
| EP-2299817-A1 | PYRIDINE CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | The University of Tennessee Research Foundation (US) | 2011-03-30 | — | — | EP | disclosed |
| US-20110046176-A1 | FURANOPYRIDINE CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2011-02-24 | — | — | US | disclosed |
| US-20110046176-A1 | FURANOPYRIDINE CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2011-02-24 | — | — | US | disclosed |
| WO-2011022692-A2 | FURANOPYRIDINE CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, THE (US) | 2011-02-24 | — | — | WO | disclosed |
| WO-2011022692-A2 | FURANOPYRIDINE CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, THE (US) | 2011-02-24 | — | — | WO | disclosed |
| WO-2009143179-A1 | PYRIDINE CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | UNIVERSIYT OF TENNESSEE RESEARCH FOUNDATION, THE (US) | 2009-11-26 | — | — | WO | disclosed |
| WO-2009143179-A1 | PYRIDINE CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | UNIVERSIYT OF TENNESSEE RESEARCH FOUNDATION, THE (US) | 2009-11-26 | — | — | WO | disclosed |
| US-20090286824-A1 | Pyridine Classical Cannabinoid Compounds and Related Methods of Use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2009-11-19 | — | — | US | disclosed |
| US-20090286824-A1 | Pyridine Classical Cannabinoid Compounds and Related Methods of Use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2009-11-19 | — | — | US | disclosed |
| US-20090286824-A1 | Pyridine Classical Cannabinoid Compounds and Related Methods of Use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046176-A1 | FURANOPYRIDINE CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | CNR1, CNR2, FAAH | PTGS2 432/4885CYP3A4 554/4885GPR84 156/4885 |
| US-20090286824-A1 | Pyridine Classical Cannabinoid Compounds and Related Methods of Use | CNR1, CNR2, NPY1R | PTGS2 1233/4885CYP3A4 483/4885GPR84 108/4885 |
| US-20120220773-A1 | PYRIDINE CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | CNR1, CNR2, NPY1R | PTGS2 1233/4885CYP3A4 483/4885GPR84 108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.