Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9584860 | 0.82 | KDM4E (0.46) | ALDH1A1SMN1; SMN2HPGDHTTL3MBTL1 | |
| SCHEMBL482954 | 0.78 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1MAPTNPSR1GLA | |
| SCHEMBL55705 | 0.78 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2HPGDHTTL3MBTL1 | |
| SCHEMBL7049447 | 0.76 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2HPGDHTTL3MBTL1 | |
| SCHEMBL6003548 | 0.76 | DRD1 (0.46) | ALDH1A1SMN1; SMN2HPGDHTTL3MBTL1 | |
| SCHEMBL4619630 | 0.76 | ALDH1A1 (0.56) | ALDH1A1HPGDL3MBTL1MAPTNPSR1 | |
| SCHEMBL3015617 | 0.76 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2HPGDHTTL3MBTL1 | |
| SCHEMBL8764972 | 0.76 | KDM4E (0.43) | ALDH1A1SMN1; SMN2HPGDHTTL3MBTL1 | |
| SCHEMBL3683087 | 0.76 | LIG1 (0.53) | ALDH1A1HPGDL3MBTL1MAPTKDM4E | |
| SCHEMBL7055886 | 0.74 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2HPGDHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756237-B1 | LATEX-ENCAPSULATED PARTICULATES FOR INK-JET APPLICATIONS | HEWLETT PACKARD DEVELOPMENT CO LP (US) | 2017-05-03 | — | — | EP | claimed |
| EP-1094826-A1 | NOVEL THERAPEUTIC AGENTS THAT MODULATE ALPHA-1A ADRENERGIC RECEPTORS | Advanced Medicine, Inc. (US) | 2001-05-02 | — | — | EP | disclosed |
| WO-1999064042-A1 | NOVEL THERAPEUTIC AGENTS THAT MODULATE ALPHA-1A ADRENERGIC RECEPTORS | ADVANCED MEDICINE, INC. (US) | 1999-12-16 | — | — | WO | disclosed |