Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.45 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6707539 | 0.78 | ALDH1A1 (0.48) | EPHX2ALDH1A1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL7045241 | 0.78 | ALDH1A1 (0.55) | EPHX2ALDH1A1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL2478440 | 0.76 | CYP2D6 (0.52) | CYP1A2CYP2D6KMT2AMAPK1LMNA | |
| SCHEMBL2777368 | 0.76 | CYP2D6 (0.52) | CYP1A2CYP2D6KMT2AMAPK1LMNA | |
| SCHEMBL14871996 | 0.76 | CYP2D6 (0.52) | CYP1A2CYP2D6KMT2AMAPK1LMNA | |
| SCHEMBL4978454 | 0.73 | ALDH1A1 (0.54) | EPHX2ALDH1A1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL15359365 | 0.73 | OPRK1 (0.47) | ALDH1A1CYP2D6HPGDKMT2AMEN1 | |
| SCHEMBL12174989 | 0.73 | OPRK1 (0.47) | ALDH1A1CYP2D6HPGDKMT2AMEN1 | |
| SCHEMBL8645113 | 0.73 | OPRK1 (0.44) | CYP3A4CYP1A2CYP2C9CYP2D6KMT2A | |
| SCHEMBL10402081 | 0.73 | OPRK1 (0.44) | CYP2D6KMT2AMEN1MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030083503-A1 | Synthesis of acylated keto amides from sulfonyl amides | FRANTZ DOUG E (US) | 2003-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030083503-A1 | Synthesis of acylated keto amides from sulfonyl amides | AADAC, ACAA2, ACSS2 | EPHX2 1779/4885ALDH1A1 512/4885CYP3A4 1159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.