SCHEMBL705016

SCHEMBL705016

CC(C)(C)[SiH2]Oc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA4 P22748 1/20 0.42
LTA4H P09960 4/20 0.39
TSHR P16473 1/20 0.39
MAPK1 P28482 1/20 0.37
RIPK1 Q13546 1/20 0.35
ALDH1A1 P00352 1/20 0.34
ALOX15 P16050 1/20 0.34
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
KCNA3 P22001 1/20 0.33
CA5A P35218 1/20 0.32
CA5B Q9Y2D0 1/20 0.32
CYP2D6 P10635 1/20 0.32
PGR P06401 1/20 0.31
LMNA P02545 1/20 0.31
HTR1D P28221 1/20 0.31
HTR1B P28222 1/20 0.31
NR1H2 P55055 1/20 0.31
BAX Q07812 1/20 0.31
MAOA P21397 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7719268 0.78 RIPK1 (0.38) CA4LTA4HTSHRMAPK1RIPK1
SCHEMBL5685404 0.76 ALDH1A1 (0.39) TSHRMAPK1ALDH1A1L3MBTL1CYP2D6
SCHEMBL1053931 0.75 LTA4H (0.39) CA4LTA4HTSHRALDH1A1KCNA3
SCHEMBL704144 0.74 ATM (0.39) CA4LTA4HTSHRRIPK1ATM
SCHEMBL16061098 0.74 LTA4H (0.34) CA4LTA4HTSHRMAPK1RIPK1
SCHEMBL706293 0.70
SCHEMBL28728642 0.70 KCNA3 (0.50) LTA4HALDH1A1KCNA3HTR1DHTR1B
SCHEMBL707758 0.69 LTA4H (0.50) CA4LTA4HTSHRALDH1A1ALOX15
SCHEMBL9162708 0.69 CA4 (0.37) CA4LTA4HTSHR
Hydrochloric Acid SCHEMBL18528255 0.69 CA4 (0.46) CA4LTA4HTSHRALDH1A1KCNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3328922-A1 HYDROXIDE-CATALYZED FORMATION OF SILICON-OXYGEN BONDS BY DEHYDROGENATIVE COUPLING OF HYDROSILANES AND ALCOHOLS California Institute of Technology (US) 2018-06-06 EP claimed
WO-2017019675-A1 HYDROXIDE-CATALYZED FORMATION OF SILICON-OXYGEN BONDS BY DEHYDROGENATIVE COUPLING OF HYDROSILANES AND ALCOHOLS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2017-02-02 WO claimed
CN-109641482-B Preparation of cis-1, 4-polydienes having multiple silane functional groups prepared by in situ hydrosilylation of polymer glues 株式会社普利司通 2021-11-05 CN disclosed
EP-2832807-A1 UNDERLAYER FILM FORMING COMPOSITION FOR SELF-ASSEMBLED FILMS Nissan Chemical Industries, Ltd. (JP) 2015-02-04 EP disclosed
US-8124239-B2 Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same FUJITSU LIMITED (JP) 2012-02-28 US disclosed
US-20100155121-A1 SILICA FILM FORMING MATERIAL, SILICA FILM AND METHOD OF MANUFACTURING THE SAME, MULTILAYER WIRING STRUCTURE AND METHOD OF MANUFACTURING THE SAME, AND SEMICONDUCTOR DEVICE AND METHOD OF MANUFACTURING THE SAME FUJITSU LIMITED (JP) 2010-06-24 US disclosed
US-7659357-B2 Precursor organosilicon polymer of 1,2-Bis(dimethylethoxysilyl)ethane, 1,4-bis(dimethylethoxysilyl)benzene, tetraethoxysilane, methyltriethoxysilane, phenyltriethoxysilane; dielectric (DE) films having etching/chemical/moisture resistance; adhesion; low DE constant; minimal wiring delay; high speed FUJITSU LIMITED (JP) 2010-02-09 US disclosed
US-20070026689-A1 Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same FUJITSU LIMITED (JP) 2007-02-01 US disclosed