Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | ALB | P02768 | 1/20 | 0.49 |
| ▸ | IL2 | P60568 | 1/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 10/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27984874 | 0.88 | ALDH1A1 (0.53) | ALDH1A1ALBIL2ITGB3FOLH1 | |
| SCHEMBL4785709 | 0.86 | MME (0.50) | ITGB3ITGA2BITGB1ITGA4FOLH1 | |
| SCHEMBL4684071 | 0.84 | ITGA4 (0.52) | ALDH1A1ALBIL2ITGB3ITGA2B | |
| SCHEMBL4684063 | 0.84 | ITGA4 (0.52) | ALDH1A1ALBIL2ITGB3ITGA2B | |
| SCHEMBL4684068 | 0.84 | ITGA4 (0.52) | ALDH1A1ALBIL2ITGB3ITGA2B | |
| SCHEMBL909810 | 0.84 | CA2 (0.51) | ALDH1A1ITGB3ITGA2BITGB1ITGA4 | |
| SCHEMBL909808 | 0.84 | CA2 (0.51) | ALDH1A1ITGB3ITGA2BITGB1ITGA4 | |
| SCHEMBL8583275 | 0.83 | CTSL (0.53) | ALBIL2ITGB3ITGA2BITGA4 | |
| SCHEMBL29107856 | 0.83 | CTSL (0.53) | ALBIL2ITGB3ITGA2BITGA4 | |
| SCHEMBL2791356 | 0.82 | ACE (0.53) | ALDH1A1ALBIL2ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301474-A2 | TYROSINE DERIVATIVES AS PHOSPHATASE INHIBITORS | Array Biopharma Inc. (US) | 2003-04-16 | — | — | EP | disclosed |
| WO-2002004412-A2 | TYROSINE DERIVATIVES AS PHOSPHATASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2002-01-17 | — | — | WO | disclosed |