Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | PTPRB | P23467 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5310322 | 0.74 | LMNA (0.37) | LMNAPIN1MAPTKDM4ECYP3A4 | |
| SCHEMBL3318225 | 0.68 | LMNA (0.45) | LMNAPIN1KDM4ECYP3A4CYP2C9 | |
| SCHEMBL27882640 | 0.66 | PIN1 (0.52) | LMNAPIN1KDM4ECYP3A4CYP2C9 | |
| SCHEMBL6187482 | 0.65 | LMNA (0.42) | LMNAPIN1KDM4ECYP3A4CYP2C9 | |
| SCHEMBL2822546 | 0.65 | KDM4E (0.50) | LMNAPIN1KDM4ECYP3A4CYP2C9 | |
| SCHEMBL5310539 | 0.63 | LMNA (0.34) | LMNAPIN1MAPTKDM4ECYP3A4 | |
| SCHEMBL4021901 | 0.61 | KDM4E (0.34) | LMNAMAPTKDM4EALDH1A1 | |
| SCHEMBL2825421 | 0.61 | NOTUM (0.41) | LMNAPIN1MAPTKDM4ECYP3A4 | |
| SCHEMBL667466 | 0.61 | LMNA (0.38) | LMNAPIN1MAPTKDM4ECYP3A4 | |
| SCHEMBL14072064 | 0.60 | ALDH1A1 (0.39) | LMNAPIN1MAPTKDM4ECYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003020877-A2 | STAINING AND SORTING GENOMES AND CHROMOSOMES USING SEQUENCE-SPECIFIC POLYAMIDES | PHARMACIA CORPORATION (US) | 2003-03-13 | — | — | WO | disclosed |