Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHF13 | Q86YI8 | 1/20 | 0.66 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | DRD3 | P35462 | 6/20 | 0.56 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CCR3 | P51677 | 1/20 | 0.46 |
| ▸ | CCR2 | P41597 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7056252 | 0.88 | DRD2 (0.70) | PHF13L3MBTL3L3MBTL1DRD3HRH4 | |
| Hydrochloric Acid SCHEMBL7058792 | 0.87 | DRD2 (0.69) | PHF13L3MBTL3L3MBTL1DRD3HRH4 | |
| SCHEMBL7055489 | 0.85 | PHF13 (0.58) | PHF13L3MBTL3L3MBTL1DRD3HRH4 | |
| SCHEMBL23682845 | 0.80 | PHF13 (1.00) | PHF13L3MBTL3L3MBTL1DRD3HRH4 | |
| SCHEMBL7056847 | 0.72 | DRD2 (0.49) | DRD3DRD2SMN1; SMN2CCR3CCR2 | |
| SCHEMBL5606683 | 0.70 | KMT2A (0.74) | MEN1KMT2A | |
| SCHEMBL19688299 | 0.70 | POLB (0.72) | PHF13L3MBTL3L3MBTL1POLBSMN1; SMN2 | |
| SCHEMBL12592289 | 0.70 | PHF13 (0.80) | PHF13L3MBTL3L3MBTL1DRD3HRH4 | |
| SCHEMBL22753440 | 0.69 | L3MBTL1 (0.67) | PHF13L3MBTL3L3MBTL1POLBSMN1; SMN2 | |
| SCHEMBL16023713 | 0.68 | HDAC4 (0.73) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003028725-A1 | 4-(1-PIPERIDINY)-BUTYLCARBOXAMIDE AS D3 DOPAMINE RECEPTOR SUBTYPE SELECTIVE LIGANDS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2003-04-10 | — | — | WO | disclosed |