Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.70 |
| ▸ | DRD3 | P35462 | 7/20 | 0.70 |
| ▸ | PHF13 | Q86YI8 | 1/20 | 0.61 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 4/20 | 0.52 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.48 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7058792 | 0.99 | DRD2 (0.69) | DRD2DRD3PHF13L3MBTL3L3MBTL1 | |
| SCHEMBL7055489 | 0.90 | PHF13 (0.58) | DRD2DRD3PHF13L3MBTL3L3MBTL1 | |
| SCHEMBL7052409 | 0.88 | PHF13 (0.66) | DRD2DRD3PHF13L3MBTL3L3MBTL1 | |
| SCHEMBL23682845 | 0.77 | PHF13 (1.00) | DRD3PHF13L3MBTL3L3MBTL1HRH4 | |
| SCHEMBL7119545 | 0.74 | DRD3 (0.64) | DRD2DRD3DRD4HTR1A | |
| SCHEMBL7055272 | 0.72 | CCR3 (0.68) | DRD2DRD3DRD4HTR1A | |
| SCHEMBL7057804 | 0.71 | DRD3 (0.63) | DRD2DRD3DRD4HTR1A | |
| SCHEMBL7056570 | 0.70 | DRD2 (1.00) | DRD2DRD3HTR1A | |
| SCHEMBL22753440 | 0.69 | L3MBTL1 (0.67) | PHF13L3MBTL3L3MBTL1 | |
| SCHEMBL9650872 | 0.69 | DRD2 (0.80) | DRD2DRD3DRD4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003028725-A1 | 4-(1-PIPERIDINY)-BUTYLCARBOXAMIDE AS D3 DOPAMINE RECEPTOR SUBTYPE SELECTIVE LIGANDS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2003-04-10 | — | — | WO | disclosed |