Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHF13 | Q86YI8 | 1/20 | 0.58 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 9/20 | 0.57 |
| ▸ | DRD2 | P14416 | 8/20 | 0.57 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.50 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.46 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7056252 | 0.90 | DRD2 (0.70) | PHF13L3MBTL3L3MBTL1DRD3DRD2 | |
| Hydrochloric Acid SCHEMBL7058792 | 0.90 | DRD2 (0.69) | PHF13L3MBTL3L3MBTL1DRD3DRD2 | |
| SCHEMBL7052409 | 0.85 | PHF13 (0.66) | PHF13L3MBTL3L3MBTL1DRD3DRD2 | |
| SCHEMBL7058610 | 0.76 | DRD3 (0.53) | DRD3DRD2DRD4SMN1; SMN2CYP1A2 | |
| SCHEMBL23682845 | 0.75 | PHF13 (1.00) | PHF13L3MBTL3L3MBTL1DRD3HRH4 | |
| SCHEMBL22753440 | 0.67 | L3MBTL1 (0.67) | PHF13L3MBTL3L3MBTL1POLBLMNA | |
| SCHEMBL7055272 | 0.66 | CCR3 (0.68) | DRD3DRD2POLBDRD4 | |
| SCHEMBL5606683 | 0.66 | KMT2A (0.74) | DRD4MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL7119545 | 0.66 | DRD3 (0.64) | DRD3DRD2DRD4SMN1; SMN2CYP1A2 | |
| SCHEMBL19688299 | 0.66 | POLB (0.72) | PHF13L3MBTL3L3MBTL1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003028725-A1 | 4-(1-PIPERIDINY)-BUTYLCARBOXAMIDE AS D3 DOPAMINE RECEPTOR SUBTYPE SELECTIVE LIGANDS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2003-04-10 | — | — | WO | disclosed |