Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 6/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.55 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.55 |
| ▸ | HTR1A | P08908 | 5/20 | 0.55 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | HTR2C | P28335 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7051595 | 0.95 | ADRA1A (0.57) | ADRA1DADRA1AADRA1BHTR1A | |
| SCHEMBL7050376 | 0.93 | ADRA1D (0.63) | ADRA1DADRA1AADRA1BHTR1ADRD3 | |
| SCHEMBL7047931 | 0.89 | HTR1A (0.59) | ADRA1DADRA1AADRA1BHTR1ADRD3 | |
| SCHEMBL7050369 | 0.89 | HTR1A (0.72) | ADRA1DADRA1AADRA1BHTR1ADRD3 | |
| SCHEMBL7683339 | 0.83 | ADRA1A (0.74) | ADRA1DADRA1AADRA1BHTR1ADRD3 | |
| SCHEMBL7051161 | 0.83 | ADRA1D (0.64) | ADRA1DADRA1AADRA1BHTR1ADRD3 | |
| SCHEMBL7048055 | 0.82 | HTR1A (0.53) | ADRA1DADRA1AADRA1BHTR1AHTR2A | |
| SCHEMBL7678716 | 0.82 | HTR1A (0.81) | ADRA1DADRA1AADRA1BHTR1ADRD3 | |
| SCHEMBL7054044 | 0.81 | HTR1A (0.69) | ADRA1DADRA1AADRA1BHTR1ADRD3 | |
| SCHEMBL8875596 | 0.79 | HTR1A (0.86) | ADRA1DADRA1AADRA1BHTR1ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1222183-B1 | BENZOPYRAN DERIVATIVES | RECORDATI CHEM PHARM (IT) | 2003-04-23 | — | — | EP | claimed |
| US-6403594-B1 | UROGENTIAL INFECTIONS, ETC | RECORDATI, S.A. CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 2002-06-11 | — | — | US | claimed |
| EP-1222183-B1 | BENZOPYRAN DERIVATIVES | RECORDATI CHEM PHARM (IT) | 2003-04-23 | — | — | EP | disclosed |
| US-6403594-B1 | UROGENTIAL INFECTIONS, ETC | RECORDATI, S.A. CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 2002-06-11 | — | — | US | disclosed |