Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 5/20 | 0.39 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7733392 | 0.79 | HTR2A (0.48) | HTR2ACYP2A6SMN1; SMN2TAAR1LOXL2 | |
| SCHEMBL11404185 | 0.78 | CYP4A11 (0.40) | HTR2AHTR2C | |
| SCHEMBL11401404 | 0.78 | HDAC1 (0.34) | HTR2AHTR2CTAAR1 | |
| SCHEMBL7050507 | 0.75 | HTR2A (0.44) | HTR2ACYP2A6SMN1; SMN2TAAR1LOXL2 | |
| SCHEMBL8212198 | 0.74 | TAAR1 (0.60) | HTR2AHTR2CCYP2A6SMN1; SMN2TAAR1 | |
| SCHEMBL22909371 | 0.73 | HRH1 (0.50) | TAAR1ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL9485195 | 0.73 | ALDH1A1 (0.52) | HTR2ACYP2A6SMN1; SMN2TAAR1LOXL2 | |
| SCHEMBL16191048 | 0.72 | HTR2A (0.51) | HTR2AHTR2CCYP2A6SMN1; SMN2TAAR1 | |
| SCHEMBL6284487 | 0.72 | TAAR1 (0.44) | HTR2ATAAR1HTR1AALOX15HSD17B10 | |
| SCHEMBL29661802 | 0.72 | TAAR1 (0.30) | TAAR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6759558-B2 | REDUCTION OF HALOGEN-SUBSTITUTED TEREPHTHALIC ACIDS AND REACTION WITH AN ALKYLATING AGENT, SULFURIC ACID, ALKYL- OR ARYLSULFONIC ACID | BAYER AKTIENGESELLSCHAFT (DE) | 2004-07-06 | — | — | US | disclosed |
| US-20020156330-A1 | Process for preparing halogen-substituted dibenzyl alcohols, these halogen-substituted dibenzyl alcohols and their use | LANXESS DEUTSCHLAND GMBH (DE) | 2002-10-24 | — | — | US | disclosed |
| US-4071570-A | ANTIARRHYTHMIC AGENTS | MERCK & CO., INC. (US) | 1978-01-31 | — | — | US | disclosed |
| US-3978127-A | ANTIARRHYTHMIC | MERCK & CO., INC. (US) | 1976-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020156330-A1 | Process for preparing halogen-substituted dibenzyl alcohols, these halogen-substituted dibenzyl alcohols and their use | ADH1A, ADH1C, ADH5 | HTR2A 2746/4885HTR2C 3070/4885CYP2A6 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.