SCHEMBL7052653

SCHEMBL7052653

COc1ccccc1C1C2CC3CC(C2)CC1C3

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 3/20 0.46
HTR2A P28223 1/20 0.46
HTR2B P41595 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.44
SLC6A2 P23975 1/20 0.44
SLC6A4 P31645 1/20 0.44
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA4 P22748 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43
CA14 Q9ULX7 1/20 0.43
MEN1 O00255 1/20 0.41
USP2 O75604 1/20 0.41
KMT2A Q03164 1/20 0.41
ALDH1A1 P00352 1/20 0.41
ADRA2B P18089 1/20 0.41
PTGS1 P23219 1/20 0.41
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9679910 0.80 HTR2C (0.42) HTR2CHTR2AHTR2BL3MBTL1SLC6A2
SCHEMBL19798400 0.79 KDM1A (0.56) SLC6A2SLC6A4KMT2A
SCHEMBL641032 0.79 HTR2C (0.43) HTR2CMEN1KMT2AALDH1A1TDP1
SCHEMBL10012213 0.77 SLC6A2 (0.32) SLC6A2SLC6A4
SCHEMBL8796050 0.76 CYP3A4 (0.35) MEN1KMT2AALDH1A1
SCHEMBL16516779 0.76 CYP3A4 (0.37) CA12CA1CA2CA9ALDH1A1
SCHEMBL645528 0.76 ALDH1A1 (0.45) MEN1KMT2AALDH1A1TDP1
SCHEMBL28318181 0.75 KDM1A (0.47) HTR2CHTR2AHTR2BSLC6A2SLC6A4
SCHEMBL9721529 0.75 HTR2C (0.42) HTR2CHTR2AHTR2BSLC6A2SLC6A4
SCHEMBL12897657 0.74 DRD2 (0.53) HTR2CMEN1KMT2AALDH1A1DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4460726-A1 NONLINEAR OPTICAL CHROMOPHORES HAVING SHORT-CHAIN BRIDGE STRUCTURES, LOW OPTICAL LOSS MATERIALS CONTAINING THE SAME, AND METHODS FOR PREPARING THE SAME Lightwave Logic, Inc. (US) 2024-11-13 EP claimed
WO-2023132934-A1 NONLINEAR OPTICAL CHROMOPHORES HAVING SHORT-CHAIN BRIDGE STRUCTURES, LOW OPTICAL LOSS MATERIALS CONTAINING THE SAME, AND METHODS FOR PREPARING THE SAME LIGHTWAVE LOGIC, INC. (US) 2023-07-13 WO claimed
US-20230212399-A1 Nonlinear Optical Chromophores Having Short-Chain Bridge Structures, Low Optical Loss Materials Containing the Same, and Methods for Preparing the Same LIGHTWAVE LOGIC, INC. (US) 2023-07-06 US claimed
US-12565587-B2 Nonlinear optical chromophores having short-chain bridge structures, low optical loss materials containing the same, and methods for preparing the same LIGHTWAVE LOGIC, INC. (US) 2026-03-03 US disclosed
EP-4460726-A1 NONLINEAR OPTICAL CHROMOPHORES HAVING SHORT-CHAIN BRIDGE STRUCTURES, LOW OPTICAL LOSS MATERIALS CONTAINING THE SAME, AND METHODS FOR PREPARING THE SAME Lightwave Logic, Inc. (US) 2024-11-13 EP disclosed
WO-2023132934-A1 NONLINEAR OPTICAL CHROMOPHORES HAVING SHORT-CHAIN BRIDGE STRUCTURES, LOW OPTICAL LOSS MATERIALS CONTAINING THE SAME, AND METHODS FOR PREPARING THE SAME LIGHTWAVE LOGIC, INC. (US) 2023-07-13 WO disclosed
US-20230212399-A1 Nonlinear Optical Chromophores Having Short-Chain Bridge Structures, Low Optical Loss Materials Containing the Same, and Methods for Preparing the Same LIGHTWAVE LOGIC, INC. (US) 2023-07-06 US disclosed
CN-112441930-A Compound, light-emitting device, light-emitting apparatus, electronic device, and lighting apparatus 株式会社半导体能源研究所 2021-03-05 CN disclosed
EP-1305306-A2 2-ADAMANTYLETHYLAMINES AND THEIR USE IN THE TREATMENT OF CONDITIONS GENERALLY ASSOCIATED WITH ABNORMALITIES IN GLUTAMATERGIC TRANSMISSION VERNALIS RESEARCH LIMITED (GB) 2003-05-02 EP disclosed
WO-2002008219-A2 2-ADAMANTYLETHYLAMINES AND THEIR USE IN THE TREATMENT OF CONDITIONS GENERALLY ASSOCIATED WITH ABNORMALITIES IN GLUTAMATERGIC TRANSMISSION VERNALIS RESEARCH LIMITED (GB) 2002-01-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12565587-B2 Nonlinear optical chromophores having short-chain bridge structures, low optical loss materials containing the same, and methods for preparing the same CRY2, GJB2, CYBA HTR2C 2399/4885HTR2A 1950/4885HTR2B 1529/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.