SCHEMBL7937191

SCHEMBL7937191

C[Si](C)(C1=Cc2ccccc2C1)c1cccc2c1Cc1ccccc1-2

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.39
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
PTGS2 P35354 2/20 0.36
MTNR1A P48039 1/20 0.35
MTNR1B P49286 1/20 0.35
DRD2 P14416 4/20 0.33
DRD4 P21917 4/20 0.33
GPR84 Q9NQS5 1/20 0.33
HTR7 P34969 1/20 0.33
HTR2B P41595 1/20 0.33
DRD3 P35462 1/20 0.32
PGR P06401 1/20 0.32
ACHE P22303 1/20 0.31
CYP11B1 P15538 1/20 0.31
CYP11B2 P19099 1/20 0.31
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30901174 1.00 PNMT (0.39) PNMTNPC1RAB9APTGS2MTNR1A
Hydrochloric Acid SCHEMBL29262831 0.97 PNMT (0.37) PNMTNPC1RAB9APTGS2MTNR1A
SCHEMBL29843943 0.83 PNMT (0.49) PNMTNPC1RAB9ADRD2DRD4
SCHEMBL61027 0.83 PNMT (0.49) PNMTNPC1RAB9ADRD2DRD4
SCHEMBL7052932 0.79 PNMT (0.38) PNMTNPC1RAB9ADRD2DRD4
SCHEMBL1452101 0.78 ACHE (0.41) PTGS2MTNR1AMTNR1BDRD2DRD4
SCHEMBL60587 0.77 PNMT (0.39) PNMTNPC1RAB9ADRD2DRD4
SCHEMBL6671922 0.76 PNMT (0.49) PNMTNPC1RAB9ADRD2DRD4
SCHEMBL5981385 0.76 PNMT (0.49) PNMTNPC1RAB9ADRD2DRD4
SCHEMBL8854215 0.76 ACHE (0.40) PTGS2MTNR1AMTNR1BDRD2DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118221849-A Application of metallocene catalyst composition as catalyst in preparation of poly alpha olefin wax 亚培烯科技(上海)有限公司 2024-06-21 CN disclosed
US-6248912-B1 OF TRANSITION METALS HAVING A TETRAHYDROINDENYL LIGAND BONDED IN THE 2-POSITION BAYER AKTIENGESELLSCHAFT (DE) 2001-06-19 US disclosed
EP-0940408-A1 Metalorganic compounds Bayer Aktiengesellschaft (DE) 1999-09-08 EP disclosed
EP-0940412-A1 Atactic propylene (co)polymers Bayer Aktiengesellschaft (DE) 1999-09-08 EP disclosed