Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK2 | O00142 | 3/20 | 0.42 |
| ▸ | TYMP | P19971 | 5/20 | 0.41 |
| ▸ | PYGM | P11217 | 1/20 | 0.38 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.37 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.37 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.36 |
| ▸ | TK1 | P04183 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7048230 | 0.92 | TK2 (0.42) | TK2TYMPPYGMRNASE1 | |
| SCHEMBL7055027 | 0.92 | TK2 (0.42) | TK2TYMPPYGMRNASE1 | |
| SCHEMBL7644575 | 0.90 | TK2 (0.45) | TK2TYMPPYGMRNASE1 | |
| SCHEMBL7052187 | 0.88 | PYGM (0.38) | TK2TYMPPYGM | |
| SCHEMBL7644973 | 0.85 | TK2 (0.44) | TK2TYMPPYGMRNASE1 | |
| SCHEMBL7053656 | 0.84 | RNASE1 (0.53) | TK2RNASE1TK1 | |
| SCHEMBL7566046 | 0.84 | RNASE1 (0.53) | TK2RNASE1TK1 | |
| SCHEMBL7644542 | 0.83 | TK2 (0.45) | TK2TYMPLGALS3LGALS4RNASE1 | |
| SCHEMBL7648742 | 0.80 | TK2 (0.43) | TK2TYMPPYGM | |
| SCHEMBL7051060 | 0.80 | TERT (0.40) | TK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1224198-B1 | NUCLEOSIDE DERIVATIVES WITH PHOTOLABILE PROTECTING GROUPS | NIGU CHEMIE GMBH (DE) | 2003-04-23 | — | — | EP | disclosed |