Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK2 | O00142 | 3/20 | 0.45 |
| ▸ | TYMP | P19971 | 5/20 | 0.42 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.41 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.36 |
| ▸ | PYGM | P11217 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7644973 | 0.92 | TK2 (0.44) | TK2TYMPRNASE1P2RY2PYGM | |
| SCHEMBL7644542 | 0.91 | TK2 (0.45) | TK2TYMPRNASE1 | |
| SCHEMBL7055027 | 0.90 | TK2 (0.42) | TK2TYMPRNASE1PYGM | |
| SCHEMBL7048230 | 0.90 | TK2 (0.42) | TK2TYMPRNASE1PYGM | |
| SCHEMBL7053660 | 0.90 | TK2 (0.42) | TK2TYMPRNASE1PYGM | |
| SCHEMBL6891984 | 0.87 | DNPH1 (0.38) | TK2P2RY2 | |
| SCHEMBL7777987 | 0.85 | TK2 (0.43) | TK2TYMPRNASE1PYGM | |
| SCHEMBL6573680 | 0.84 | RNASE1 (0.59) | TK2RNASE1 | |
| SCHEMBL6572381 | 0.84 | RNASE1 (0.59) | TK2RNASE1 | |
| SCHEMBL6891122 | 0.82 | P2RY6 (0.38) | P2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212338-B1 | Nucleoside derivatives with photolabile protective groups | DEUTSCHES KREBSFORSCH (DE) | 2012-11-21 | — | — | EP | disclosed |
| EP-0797580-B1 | NUCLEOSIDE DERIVATIVES WITH PHOTOLABILE PROTECTIVE GROUPS | PFLEIDERER WOLFGANG (DE) | 2002-04-10 | — | — | EP | disclosed |