Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 3/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | SCN1A | P35498 | 2/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HRH1 | P35367 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1040114 | 0.79 | CES2 (0.38) | TSHRCES2CES1HTR2ATAAR1 | |
| SCHEMBL366711 | 0.77 | L3MBTL1 (0.47) | TSHRHTR2ATAAR1CYP2D6LMNA | |
| SCHEMBL7662943 | 0.77 | CES2 (0.37) | TSHRCES2CES1HTR2ATAAR1 | |
| SCHEMBL30231920 | 0.76 | SCN1A (0.50) | TSHRHTR2ACYP2D6LMNACYP1A2 | |
| SCHEMBL6512285 | 0.76 | CHRM2 (0.37) | TSHRCES2CES1HTR2ATAAR1 | |
| SCHEMBL790660 | 0.76 | SLC6A2 (0.47) | TSHRCYP2D6CYP1A2SMN1; SMN2HTT | |
| SCHEMBL11247443 | 0.74 | TSHR (0.46) | TSHRHTR2ATAAR1CYP2D6LMNA | |
| SCHEMBL9642930 | 0.74 | LMNA (0.41) | TSHRHTR2ACYP2D6LMNACYP1A2 | |
| SCHEMBL4025487 | 0.74 | ALDH1A1 (0.43) | TSHRCES2CES1HTR2ACYP2D6 | |
| SCHEMBL9662373 | 0.74 | TSHR (0.41) | TSHRHTR2ACYP2D6LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1304325-A1 | 5-(M-CYANOBENZYLAMINO)PYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-04-23 | — | — | EP | disclosed |